ArticleHuman brain mapping2021
Redundancy circuits of the commissural pathways in human and rhesus macaque brains.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Multilevel white matter degeneration associated cognitive dysfunction in mild cognitive impairment.Molecular psychiatry · 2026Article
- Potentiation of cortico-spinal output via targeted electrical stimulation of the motor thalamus.Nature communications · 2024Article
- POTENTIATION OF CORTICO-SPINAL OUTPUT VIA TARGETED ELECTRICAL STIMULATION OF THE MOTOR THALAMUS.medRxiv : the preprint server for health sciences · 2023Article
- The connectional anatomy of visual mental imagery: evidence from a patient with left occipito-temporal damage.Brain structure & function · 2022Article
- Population-based tract-to-region connectome of the human brain and its hierarchical topology.Nature communications · 2022Article
- Network Diffusion Embedding Reveals Transdiagnostic Subnetwork Disruption and Potential Treatment Targets in Internalizing Psychopathologies.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Redundancy circuits of the commissural pathways in human and rhesus macaque brains.Human brain mapping · 2021Article
- A Comparative Study of Diffusion Fiber Reconstruction Models for Pyramidal Tract Branches.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
It has been hypothesized that the human brain has less redundancy than animals, but the structural evidence has not been identified to confirm this claim. Here, we report three redundancy circuits of the commissural pathways in primate brains, namely the orbitofrontal, temporal, and occipital redundancy circuits of the anterior commissure and corpus callosum. Each redundancy circuit has two distinctly separated routes connecting a common pair of cortical regions. We mapped their trajectories in human and rhesus macaque brains using individual and population-averaged tractography. The dissection results confirmed the existence of these redundancy circuits connecting the orbitofrontal lobe, amygdala, and visual cortex. The volume analysis showed a significant reduction in the orbitofrontal and occipital redundancy circuits of the human brain, whereas the temporal redundancy circuit had a substantial organizational difference between the human and rhesus macaque. Our results support the hypothesis that the human brain has less redundancy in the commissural pathways than that of the rhesus macaque brain. Further studies are needed to explore its neuropathological implications.
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