ArticleJournal of veterinary internal medicine2021
Peri-ictal magnetic resonance imaging characteristics in dogs with suspected idiopathic epilepsy.
Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- Assessment of Oxidative Stress-Related Markers and Inflammatory Proteins in Serum and CSF Samples of Dogs with Different Types of Epilepsy.Antioxidants (Basel, Switzerland) · 2026Article
- A multicenter retrospective analysis of canine idiopathic epilepsy in China.Frontiers in veterinary science · 2026Article
- Cerebrospinal fluid markers and magnetic resonance imaging lesion volume predicting relapse in canine meningoencephalitis of unknown origin.Frontiers in veterinary science · 2026Article
- Peritumoral Edema in Canine Extra-Axial Brain Tumours: Effect of Steroids.Veterinary and comparative oncology · 2025Article
- Peritumoral MRI findings and brain herniations in epileptic dogs with prosencephalic brain tumors: a multicentre retrospective study.Frontiers in veterinary science · 2025Article
- Cellular localization of a variant RAPGEF5 protein associated with idiopathic epilepsy risk in the Belgian shepherd.Canine medicine and genetics · 2024Article
- Magnetic resonance imaging in canine idiopathic epilepsy: a mini-review.Frontiers in veterinary science · 2024Review
- High-field MRI findings in epileptic dogs with a normal inter-ictal neurological examination.Frontiers in veterinary science · 2024Article
- Diffusion tensor imaging for detecting biomarkers of idiopathic epilepsy in dogs.Frontiers in veterinary science · 2024Review
- Comparative subcutaneous and submuscular implantation of an electroencephalography device for long term electroencephalographic monitoring in dogs.Frontiers in veterinary science · 2024Article
- Diagnostic value of cerebrospinal fluid analysis in epileptic cats with unremarkable brain MRI or hippocampal signal changes only.Journal of feline medicine and surgery · 2023Article
- Periodic discharges in veterinary electroencephalography-A visual review.Frontiers in veterinary science · 2023Review
- Diffusion tensor-based analysis of white matter in dogs with idiopathic epilepsy.Frontiers in veterinary science · 2023Article
- Treatment of intracranial neoplasia in dogs using higher doses: A randomized controlled trial comparing a boosted to a conventional radiation protocol.Journal of veterinary internal medicine · 2022Article
- Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs.Journal of veterinary internal medicine · 2022Article
- Single-Voxel Proton Magnetic Resonance Spectroscopy of the Thalamus in Idiopathic Epileptic Dogs and in Healthy Control Dogs.Frontiers in veterinary science · 2022Article
- Ketamine administration in idiopathic epileptic and healthy control dogs: Can we detect differences in brain metabolite response with spectroscopy?Frontiers in veterinary science · 2022Article
- Phenotypic characterization of idiopathic epilepsy and epilepsy of unknown cause in Irish Setters.Frontiers in veterinary science · 2022Article
- Dogs as a Natural Animal Model of Epilepsy.Frontiers in veterinary science · 2022Review
- Peri-ictal magnetic resonance imaging characteristics in dogs with suspected idiopathic epilepsy.Journal of veterinary internal medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pathophysiology of changes in magnetic resonance imaging (MRI) detected after a seizure is not fully understood.
objectiveTo characterize and describe seizure-induced changes detected by MRI. ANIMALS: Eighty-one client-owned dogs diagnosed with idiopathic epilepsy.
methodsData collected retrospectively from medical records and included anatomical areas affected, T1-, T2-weighted and T2-FLAIR (fluid-attenuated inversion recovery) appearance, whether changes were unilateral or bilateral, symmetry, contrast enhancement, mass effect, and, gray and white matter distribution. Diffusion- and perfusion weighted maps were evaluated, if available.
resultsSeizure-induced changes were T2-hyperintense with no suppression of signal on FLAIR. Lesions were T1-isointense (55/81) or hypointense (26/81), local mass effect (23/81) and contrast enhancement (12/81). The majority of changes were bilateral (71/81) and symmetrical (69/71). The most common areas affected were the hippocampus (39/81) cingulate gyrus (33/81), hippocampus and piriform lobes (32/81). Distribution analysis suggested concurrence between cingulate gyrus and pulvinar thalamic nuclei, the cingulate gyrus and parahippocampal gyrus, hippocampus and piriform lobe, and, hippocampus and parahippocampal gyrus. Diffusion (DWI) characteristics were a mixed-pattern of restricted, facilitated, and normal diffusion. Perfusion (PWI) showed either hypoperfusion (6/9) or hyperperfusion (3/9). CONCLUSIONS AND CLINICAL IMPORTANCE: More areas, than previously reported, have been identified that could incur seizure-induced changes. Similar to human literature, DWI and PWI changes have been identified that could reflect the underlying metabolic and vascular changes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.