Evidence map›Paper›PMID 33559830›Full record

ArticleNeurochemical research2021

MiR-101a-3p Attenuated Pilocarpine-Induced Epilepsy by Downregulating c-FOS.

Jiefeng Geng, Haibiao Zhao, Xing Liu, Junjie Geng, Yuyuan Gao, Bingzheng He

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. P/Q type (CaMolecular neurobiology · 2024
    Article
  5. Review
  6. Article
  7. Aberrant expression of miRNAs in epilepsy.Molecular biology reports · 2022
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jiefeng Geng *Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Rd, Zhengzhou, 450052, Henan, China. gjf18203671301@163.com.
Haibiao Zhao *Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Rd, Zhengzhou, 450052, Henan, China.
Xing LiuDepartment of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Junjie GengDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Rd, Zhengzhou, 450052, Henan, China.
Yuyuan GaoDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Rd, Zhengzhou, 450052, Henan, China.
Bingzheng HeDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Rd, Zhengzhou, 450052, Henan, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore the effects and function of microRNA-101a-3p (miR-101a-3p) in epilepsy. Rat model of pilocarpine-induced epilepsy was established and the seizure frequency was recorded. Expression of miR-101a-3p and c-Fos in hippocampus tissues of Rat models were detected by qRT-PCR and western blot. Besides, we established a hippocampal neuronal culture model of acquired epilepsy using Mg

Indexed as

AnimalsApoptosisAutophagyCell SurvivalDown-RegulationEpilepsyHippocampusMicroRNAsNeuronsPilocarpineProto-Oncogene Proteins c-fosRatsRats, Sprague-DawleyUp-RegulationMicroRNAsMIRN101 microRNA, ratPilocarpineProto-Oncogene Proteins c-fosc-FOSmiR-101a-3pPilocarpine-induced epilepsy

Identifiers

PMID33559830
OpenAlexW3128617328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.