Evidence map›Paper›PMID 33559811›Full record

ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2021

Effect of the hydroxamate group in the antitumoral activity and toxicity toward normal cells of new copper(II) complexes.

Nathália F B Azeredo, Franz V Borges, Marcelo S Mathias, Jackson A L C Resende, Roberto W A Franco, Milton M Kanashiro, Adolfo Horn, Christiane Fernandes

Abstract read
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In one paragraph

Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nathália F B AzeredoLaboratório de Ciências Químicas, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Franz V BorgesInstituto Federal Fluminense, Campos dos Goytacazes, RJ, 28030-130, Brazil.
Marcelo S MathiasLaboratório de Ciências Químicas, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Jackson A L C ResendeInstituto de Ciências Exatas e da Terra, Campus Universitário do Araguaia, Universidade Federal de Mato Grosso (UFMT), Barra do Garças, MT, Brazil.
Roberto W A FrancoLaboratório de Ciências Físicas, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Milton M KanashiroLaboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Adolfo HornDepartamento de Química, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Christiane FernandesDepartamento de Química, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil. christiane.horn@ufsc.br.ORCID 0000-0002-9597-2966
State University of Norte Fluminense · BRUniversidade Federal de Santa Catarina · BRInstituto Federal Fluminense · BRUniversidade Federal de Mato Grosso · BR

Funding

CNPq 000FAPERJ 000
6 · The paper itself

Abstract

The synthesis, physico-chemical characterization and cytotoxicity of four copper(II) coordination complexes, i.e. [Cu(HBPA)Cl

Indexed as

Antineoplastic AgentsCell ProliferationCells, CulturedCell SurvivalCoordination ComplexesCopperDrug Screening Assays, AntitumorHumansHydroxamic AcidsAntineoplastic Agentsbenzohydroxamic acidCoordination ComplexesCopperHydroxamic AcidsAntitumor activityApoptosisBenzo hydroxamic acid (HBHA)Copper(II) complexPBMC

Identifiers

PMID33559811
OpenAlexW3128471013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.