Evidence map›Paper›PMID 33559801›Full record

ArticleFish physiology and biochemistry2021

Light-induced and circadian expressions of melanopsin genes opn4xa and opn4xb in the eyes of juvenile grass puffer Takifugu alboplumbeus.

Takashi Kitahashi, Daisuke Kurokawa, Shouzo Ogiso, Nobuo Suzuki, Hironori Ando

Abstract read
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In one paragraph

Article in Fish physiology and biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Takashi KitahashiSado Marine Biological Station, Sado Island Center for Ecological Sustainability, Niigata University, 87 Tassha, Sado-shi, Niigata, 952-2135, Japan. takashi.kitahashi@gmail.com.ORCID https://orcid.org/0000-0003-0512-7548
Daisuke KurokawaMisaki Marine Biological Station, Graduate School of Science, The University of Tokyo, 1024 Koajiro, Misaki, Miura, Kanagawa, 238-0225, Japan.
Shouzo OgisoNoto Marine Laboratory, Institute of Nature and Environmental Technology, Kanazawa University, 4-1 Mu, Ogi, Noto-cho, Ishikawa, 927-0553, Japan.
Nobuo SuzukiNoto Marine Laboratory, Institute of Nature and Environmental Technology, Kanazawa University, 4-1 Mu, Ogi, Noto-cho, Ishikawa, 927-0553, Japan.
Hironori AndoSado Marine Biological Station, Sado Island Center for Ecological Sustainability, Niigata University, 87 Tassha, Sado-shi, Niigata, 952-2135, Japan.
Kanazawa University · JPNiigata University · JPTakahashi Industrial and Economic Research Foundation · JPThe University of Tokyo · JP

Funding

Institute of Nature and Environmental Technology, Kanazawa University 17016Institute of Nature and Environmental Technology, Kanazawa University 18019Japan Society for the Promotion of Science 16H04812HJapan Society for the Promotion of Science 17K07486
6 · The paper itself

Abstract

Animals regulate a variety of aspects of physiology according to environmental light conditions via nonvisual opsins such as melanopsin. In order to study photic regulation of fish physiology, expression changes of the genes for melanopsin (opn4xa and opn4xb) and effects of light on them were examined in juvenile grass puffer Takifugu alboplumbeus using quantitative real-time PCR. In the brain of juvenile fish, no significant diurnal nor circadian changes were observed in opn4x mRNA levels. On the other hand, in the eyes, the mRNA level of opn4xa showed a significant diurnal rhythm with a peak at Zeitgeber time (ZT) 4, while no apparent circadian changes were observed. The mRNA level of opn4xb in the eyes showed a diurnal change similar to that of opn4xa, while it showed a significant circadian change. Furthermore, continuous exposure to light during a subjective night significantly increased the mRNA levels of opn4xa in the eyes at ZT24, suggesting that light induces gene expression of opn4xa in the eyes and that the induction occurs only during the night-day transition period. These results suggest that Opn4xa and Opn4xb play differential roles in the eyes of juvenile grass puffer to mediate the physiological effects of environmental light information.

Indexed as

Circadian RhythmLightAgingAnimalsCloning, MolecularEyeFemaleGene Expression Regulation, DevelopmentalMelanopsinPhylogenyRNA, MessengerRod OpsinsTakifuguTissue DistributionMelanopsinRNA, MessengerRod OpsinsBiological clockCircadian rhythmDiurnal rhythmLightMelanopsinPhotoreceptor

Identifiers

PMID33559801
OpenAlexW3126831822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.