Evidence map›Paper›PMID 33559787›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2021

Cost-effectiveness of the latent tuberculosis screening program for migrants in Stockholm Region.

Jad Shedrawy, Charlotte Deogan, Joanna Nederby Öhd, Maria-Pia Hergens, Judith Bruchfeld, Jerker Jonsson, Andrew Siroka, Knut Lönnroth

Abstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
  5. Article
  6. The prevalence of tuberculosis infection among foreign-born Canadians: a modelling study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  7. Article
  8. Article
  9. Review
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jad ShedrawyDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden. jad.shedrawy@ki.se.
Charlotte DeoganDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Joanna Nederby ÖhdDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Maria-Pia HergensDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Judith BruchfeldDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Jerker JonssonThe Public Health Agency of Sweden, Stockholm, Sweden.
Andrew SirokaWorld Health Organization, Geneva, Switzerland.
Knut LönnrothDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionThe majority of tuberculosis (TB) cases in Sweden occur among migrants from endemic countries through activation of latent tuberculosis infection (LTBI). Sweden has LTBI-screening policies for migrants that have not been previously evaluated. This study aimed to assess the cost-effectiveness of the current screening strategy in Stockholm.

methodsA Markov model was developed to predict the costs and effects of the current LTBI-screening program compared to a scenario of no LTBI screening over a 50-year time horizon. Epidemiological and cost data were obtained from local sources when available. The primary outcomes were incremental cost-effectiveness ratio (ICER) in terms of societal cost per quality-adjusted life year (QALY).

resultsScreening migrants in the age group 13-19 years had the lowest ICER, 300,082 Swedish Kronor (SEK)/QALY, which is considered cost-effective in Sweden. In the age group 20-34, ICER was 714,527 SEK/QALY (moderately cost-effectives) and in all age groups above 34 ICERs were above 1,000,000 SEK/QALY (not cost-effective). ICER decreased with increasing TB incidence in country of origin.

conclusionScreening is cost-effective for young cohorts, mainly between 13 and 19, while cost-effectiveness in age group 20-34 years could be enhanced by focusing on migrants from highest incidence countries and/or by increasing the LTBI treatment initiation rate. Screening is not cost-effective in older cohorts regardless of the country of origin.

Indexed as

Latent TuberculosisTransients and MigrantsTuberculosisAdolescentAdultAgedCost-Benefit AnalysisHumansMass ScreeningQuality-Adjusted Life YearsYoung AdultCost-effectivenessLatent tuberculosisMigrantsScreening

Identifiers

PMID33559787
PMCPMC7954754

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.