Evidence map›Paper›PMID 33559771›Full record

ArticleArchives of osteoporosis2021

Predictors of circulating vitamin D levels in healthy mid-life Singaporean women.

Wei Fun Cheong, Shanshan Ji, Amaury Cazenave-Gassiot, Win Pa Pa Thu, Susan Logan, Jane Cauley, Michael S Kramer, Eu-Leong Yong

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Wei Fun CheongDepartment of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, 1E Kent Ridge Road, Level 12, Singapore, 119228, Republic of Singapore.
Shanshan JiSingapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, 117456, Republic of Singapore.
Amaury Cazenave-GassiotSingapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, 117456, Republic of Singapore.
Win Pa Pa ThuDepartment of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, 1E Kent Ridge Road, Level 12, Singapore, 119228, Republic of Singapore.
Susan LoganDepartment of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, 1E Kent Ridge Road, Level 12, Singapore, 119228, Republic of Singapore.
Jane CauleyDepartment of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, USA.
Michael S KramerDepartments of Epidemiology, Biostatistics & Occupational Health and of Pediatrics, Faculty of Medicine, McGill University, Montreal, Quebec, H3G 1Y6, Canada.
Eu-Leong YongDepartment of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, 1E Kent Ridge Road, Level 12, Singapore, 119228, Republic of Singapore. obgyel@nus.edu.sg.ORCID https://orcid.org/0000-0001-6511-770X
National University of Singapore · SGMcGill University Health Centre · CAUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D levels were lowest in Indian and Malay compared to Chinese women, and in younger and employed women. The main reason for hypovitaminosis D in study women was deficient cutaneous production. Supplementation in regions with abundant sunshine should consider ethnicity and opportunities for exposure to sunlight.

introductionLittle is known about variations in circulating vitamin D levels in multiethnic mid-life women living in communities with year-round sunlight. Our study describes the circulating vitamin D levels and their sociodemographic predictors in mid-life Singaporean women.

methodsProspective cross-sectional study of healthy Singaporean women, age 45-69 years, who were not consuming vitamin D supplements. Total 25-hydroxyvitaminD [25(OH)D], the sum of 25(OH)D

resultsThe analytic cohort of 721 women, mean age 55.2±6.0 (±SD) years, was of Chinese (82%), Indian (11%), and Malay (7%) ethnicity. Their mean 25(OH)D level was 24.8±7.8ng/mL. One-third (32.6%) of the women had deficient 25(OH)D (≤20ng/mL) and 3.5% were severely deficient (<12ng/mL). 25(OH)D

conclusionOne-third of mid-life Singaporean women were 25(OH)D deficient, and the major independent predictors of deficiency were Indian or Malay ethnicity and younger age. Vitamin D supplementation in mid-life women should be targeted to those with documented deficiency or limited cutaneous production.

Indexed as

Vitamin DVitamin D DeficiencyAgedCross-Sectional StudiesDietary SupplementsFemaleHumansMiddle AgedProspective StudiesVitaminsVitamin DVitamins25-hydroxyvitamin DDeficiencyEthnic differencesRisk factorsVitamin D

Identifiers

PMID33559771
OpenAlexW3126960230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.