Evidence map›Paper›PMID 33559758›Full record

ArticleApplied biochemistry and biotechnology2021

In Vitro Detected hly II Cytotoxin in a Strain of Staphylococcus aureus (BM S-2) and Plant-Derived Aromatic Components: a Molecular Docking Study.

Debadarshee Das Mohapatra, Smaranika Pattnaik, Sruti Panda

Abstract read
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In one paragraph

Article in Applied biochemistry and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Macrolactin A as a Novel Inhibitory Agent for SARS-CoV-2 MApplied biochemistry and biotechnology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Debadarshee Das Mohapatra *Dept. of Mathematics, BITS-PILANI, Hyderabad Campus, Hyderabad, India.
Smaranika Pattnaik *Laboratory of Medical Microbiology, School of Life Sciences, Sambalpur University, Sambalpur, India. smaranika2010@gmail.com.
Sruti Panda *MITS School of Biotechnology, Bhubaneswar, India.
Birla Institute of Technology and Science - Hyderabad Campus · INSambalpur University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In time, diagnosis and detection of virulence factor and its pathogenomics study continues to grow and this leads to novel treatments for infectious diseases. The objective of this study was to detect and characterise virulence genes in a haemolytic strain of Staphylococcus aureus in vitro and molecular interaction studies with herbal essential oil components in silico. A hospital biosample-isolated strain of Staphylococcus aureus (BMS-2) was resistant towards Cephalosporin. The PCR-amplified FASTA nucleotide sequence was identical with S. aureus strains absolutely. The calculated GC value was 34.05%. The translated protein sequence was identified with a conserved domain of hlyII β-channel forming cytolysin belonging to leukocidin superfamily and was predicted as a stable, non-transmembrane protein comprising B cell epitopes. Structurally, the protein was found to be composed of α helix, π-helix, extended strands, β-sheet, turn and bends with atomic composition as C

Indexed as

Molecular Docking SimulationBacterial ProteinsHumansOils, VolatilePerforinProtein Structure, SecondaryStaphylococcus aureusBacterial ProteinsOils, VolatilePerforinEssential oil componentshly II cytotoxinIn vitro detectionMolecular dockingα-Haemolysis

Identifiers

PMID33559758
OpenAlexW3126860064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.