Evidence map›Paper›PMID 33559723›Full record

ArticleArchives of orthopaedic and trauma surgery2021

Should all hip and knee prosthetic joints be aspirated prior to revision surgery?

Femke Staphorst, Paul C Jutte, Alexander L Boerboom, Greetje A Kampinga, Joris J W Ploegmakers, Marjan Wouthuyzen-Bakker

Open access · hybridAbstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Prevalence, interpretation, and management of unexpected positive cultures in revision TKA: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Femke StaphorstDepartment of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.
Paul C JutteDepartment of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Alexander L BoerboomDepartment of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Greetje A KampingaDepartment of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.
Joris J W PloegmakersDepartment of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Marjan Wouthuyzen-BakkerDepartment of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands. m.wouthuyzen-bakker@umcg.nl.
University of Groningen · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsIt is essential to exclude a periprosthetic joint infection (PJI) prior to revision surgery. It is recommended to routinely aspirate the joint before surgery. However, this may not be necessary in a subgroup of patients. The aim of our study was to investigate if specific clinical and implant characteristics could be identified to rule out a PJI prior to revision surgery.

methodsWe retrospectively evaluated clinical and implant characteristics of patients who underwent a hip or knee revision surgery between October 2015 and October 2018. Patients were diagnosed with a PJI according to the MSIS diagnostic criteria.

resultsA total of 156 patients were analyzed, including 107 implants that were revised because of prosthetic loosening and 49 because of mechanical failure (i.e. instability, malalignment or malpositioning). No PJI was diagnosed in the group with mechanical failure. In the prosthetic loosening group, 20 of 107 were diagnosed with a PJI (19%). Although there was a significantly lower chance of having a PJI with an implant age of > 5 years combined with a CRP < 5 mg/L, an infection was still present in 3 out of 39 cases (8%).

conclusionImplants with solely mechanical failure without signs of loosening and low inflammatory parameters probably do not require a synovial fluid aspiration. These results need to be confirmed in a larger cohort of patients. In case of prosthetic loosening, all joints need to be aspirated before surgery as no specific characteristic could be identified to rule out an infection.

Indexed as

ParacentesisArthroplasty, Replacement, HipArthroplasty, Replacement, KneeHip JointHumansKnee JointProsthesis FailureProsthesis-Related InfectionsReoperationRetrospective StudiesAseptic looseningAspirationMechanical failurePeriprosthetic joint infectionRevision surgery

Identifiers

PMID33559723
PMCPMC7900020
OpenAlexW3129046303

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.