ArticleJournal of the American Heart Association2021
Trends of Ruptured and Unruptured Aneurysms Treatment in the United States in Post-ISAT Era: A National Inpatient Sample Analysis.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Clinical management of contrast-induced neurotoxicity: a systematic review.Acta neurologica Belgica · 2024Pooled it
- M1 segment morphology is associated with far lateral lenticulostriate arteries in middle cerebral artery bifurcation surgery: a cadaveric and clinical anatomic study.Neurosurgical review · 2026Article
- Incidence of postoperative seizures after clipping of unruptured intracranial aneurysms without prophylactic antiseizure medications: a prospective noninferiority cohort study.Neurosurgical review · 2026Article
- Technique and device specific diffusion-weighted imaging detected ischemic lesions and occlusion outcomes in endovascular treatment of unruptured aneurysms.Acta neurochirurgica · 2026Article
- Woven EndoBridge versus stent-assisted coil embolization for the treatment of ruptured wide-necked aneurysms: A multicentric experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- What preoperative testing is needed in patients undergoing treatment for unruptured intracranial aneurysms? Optimizing value-based care based on perioperative risk: a cost effectiveness analysis.Neurosurgical review · 2026Article
- A review and journey in intrasaccular treatment of intracranial aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Review
- Comparative analysis of surgical and endovascular aneurysm repair in subarachnoid hemorrhage: a single-center study with 1,171 patients.Acta neurochirurgica · 2025Article
- Circumferential Aneurysm Wall Enhancement Predicts Recanalization After Stent-Assisted Coiling in Small Unruptured Intracranial Aneurysms.Brain and behavior · 2025Article
- Cost-effectiveness analysis of MRA screening for cerebral aneurysms in Black and Hispanic women: A high risk population.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Treatment of small intracranial aneurysms using the SMALLSS scoring system: a novel system for decision making.Acta neurochirurgica · 2025Article
- Has a fast treatment transition from surgical to endovascular operations improved the survival of aneurysmal subarachnoid hemorrhage?Acta neurochirurgica · 2025Article
- Treatment of Spontaneous Subarachnoid Hemorrhage: A 20-Year National Inpatient Sample Review.Stroke (Hoboken, N.J.) · 2025Article
- From knife to needle - the trend of vascular neurosurgery in Belgium.Brain & spine · 2025Article
- Endovascular surgical neuro-oncology: advancing a new subspecialty.Journal of neuro-oncology · 2024Review
- Successful Surgical Management of a Ruptured Intracranial Aneurysm in a Nine-Month-Old Male: A Rare Pediatric Case.Cureus · 2024Article
- Clinical and Hemodynamic Features of Aneurysm Rupture in Coil Embolization of Intracranial Aneurysms.Diagnostics (Basel, Switzerland) · 2024Article
- Changes in treatment of intracranial aneurysms during the last decade in a large European neurovascular center.Acta neurochirurgica · 2024Observational
- Cerebral aneurysms: Germany-wide real-world outcome data of endovascular or neurosurgical treatment from 2007 to 2019.Journal of neurointerventional surgery · 2024Article
- Epidemiology and treatment of atraumatic subarachnoid hemorrhage over 10 years in a population-based registry.European stroke journal · 2024Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background The ISAT (International Subarachnoid Aneurysm Trial) has generated a paradigm shift towards endovascular treatment for intracranial aneurysms but remains unclear if this has led to a true reduction in the risk for aneurysmal subarachnoid hemorrhage (aSAH). We sought to study the association between the treatment burden of unruptured and ruptured aneurysms in the post-ISAT era. Methods and Results Admissions data from the National Inpatient Sample (2004-2014) were extracted, including patients with a primary diagnosis of aSAH or unruptured intracranial aneurysms treated by clipping or coiling. Within each year, this combined group was randomly matched to non-aneurysmal control group, based on age, sex, and Elixhauser comorbidity index. Multinomial regression was performed to calculate the relative risk ratio of undergoing treatment for either ruptured or unruptured aneurysms in comparison with the reference control group, adjusted for time. After adjusting for National Inpatient Sample sampling effects, 243 754 patients with aneurysm were identified, 174 580 (71.6%) were women; mean age, 55.4±13.2 years. A total of 121 882 (50.01%) patients were treated for unruptured aneurysms, 79 627 (65.3%) endovascularly and 42 256 (34.7%) surgically. A total of 121 872 (49.99%) patients underwent procedures for aSAH, 68 921 (56.6%) endovascular, and 52 951 (43.5%) surgically. Multinomial regression revealed a significant year-to-year decrease in aSAH procedures compared with the control group of non-aneurysmal hospitalizations (relative risk ratio, 0.963 per year;
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