ArticleJournal of gynecologic oncology2021
The first-round results of a population-based cohort study of HPV testing in Japanese cervical cancer screening: baseline characteristics, screening results, and referral rate.
Article in Journal of gynecologic oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Evaluation of colposcopy after the addition of human papillomavirus testing to the Turkish cervical cancer screening program.Cancer medicine · 2023Article
- Validation of HPV triage in cytology-based cervical cancer screening for ASC-US cases using Japanese data.Journal of gynecologic oncology · 2023Article
- Lower accuracy of cytological screening for high-grade squamous intraepithelial neoplasia in women over 50 years of age in Japan.International journal of clinical oncology · 2022Article
- Comparison between Urine and Cervical High-Risk HPV Tests for Japanese Women with ASC-US.Diagnostics (Basel, Switzerland) · 2021Article
- Human papillomavirus testing as a primary screening tool for cervical cancer.Journal of gynecologic oncology · 2021Article
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10 authors.
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Abstract
objectiveIn 2013, a cohort study aimed to clarify the positive and negative effects of introducing the human papillomavirus (HPV) testing for population-based cervical cancer screening has been launched in Japan. This study included four screenings during the subsequent 7-year follow-up period. We aim to describe the results of the first round of this study on cervical cancer screening here.
methodsThis study began in September 2013 with recruitment completed in March 2016. Women aged 30-49 years were divided into 2 groups: those who received uterine cervical cytology alone in the first year (control group), or those who received a combination of cytology and HPV testing (intervention group), based on their age. After first screening, women with positive result of cytology or positive HPV test required referral. We summarized the results of the first round of cervical cancer screening.
resultsOf the 25,074 women who were eligible for the study, 13,845 women (55.2%) were screened with cytology alone; 11,229 women (44.8%) received a combination of cytology and HPV testing. After screening, 407 women (2.9%) in the control group and 1,003 women (8.9%) in the intervention group required referral, respectively. Adding HPV testing increased referral rate significantly (p<0.001).
conclusionAfter first screening, introduction of HPV testing appears to contribute to significantly higher referral rates, suggesting that the number of colposcopies as a detailed examination may increase. These preliminary findings suggest that if HPV testing is introduced into screening, medical institutions need to be prepared for an increasing number of follow-up examinations.
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