Evidence map›Paper›PMID 33559344›Full record

ReviewJournal of the European Academy of Dermatology and Venereology : JEADV2021

Trichodysplasia spinulosa: a comprehensive review of the disease and its treatment.

P Curman, A Näsman, H Brauner

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of the European Academy of Dermatology and Venereology : JEADV, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Trichodysplasia Spinulosa.Sultan Qaboos University medical journal · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. [Human polyomavirus-associated skin diseases].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2022
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

P CurmanDermatology and Venereology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-2051-8491
A NäsmanDepartment of Clinical Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden.
H BraunerDermato-Venereology Clinic, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-2810-4189
Karolinska University Hospital · SE

Funding

Åke Wiberg Stiftelse M19-0665Cancerfonden 19 0408 FkCancer och AllergifondenJeanssons StiftelserKarolinska Institutet 2018-02203Magnus Bergvalls Stiftelse 2019-03538Stiftelsen Clas Groschinskys Minnesfond M19390Stiftelsen TornspiranStockholms Läns Landsting 20190859Svenska Sällskapet för Medicinsk Forskning S17-0104
6 · The paper itself

Abstract

Trichodysplasia spinulosa (TS) is a rare dermatological disease caused by TS-associated polyomavirus (TSPyV) in immunosuppressed patients. The seroprevalence of TSPyV in immunocompetent adults is high and the number of immunosuppressed patients developing TS remains low, suggesting that TS is underdiagnosed and/or that additional unknown factors are needed in order to develop TS. There is no well-established treatment for TS, and to date a majority of reported cases have consequently received ineffective therapies, likely due to the unavailability of reviews and recommendations of treatments for TS. The few treatments reported in case reports to be effective include topical cidofovir 3%, reduction of immunosuppression and oral valganciclovir. In this comprehensive review, we present all published cases to date, together with a summary of all treatments for TS categorized by overall clinical efficacy, thus addressing this rare disease and what appears to be its clinically efficacious treatment.

Indexed as

Hair DiseasesPolyomavirusPolyomavirus InfectionsAdultDNA, ViralHumansSeroepidemiologic StudiesDNA, Viral

Identifiers

PMID33559344
PMCPMC8247895
OpenAlexW3111589772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.