Evidence map›Paper›PMID 33559264›Full record

ArticleMicrobial biotechnology2022

Activity of bacteria isolated from bats against Pseudogymnoascus destructans in China.

Zhongle Li, Aoqiang Li, Joseph R Hoyt, Wentao Dai, Haixia Leng, Yanfei Li, Wei Li, Sen Liu, Longru Jin, Keping Sun and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microbial biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

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  9. Complete genome sequences of two strains ofMicrobiology resource announcements · 2025
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  12. Variation and assembly mechanisms ofMicrobiology spectrum · 2025
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  13. A Palearctic view of a bat fungal disease.Conservation biology : the journal of the Society for Conservation Biology · 2025
    Review
  14. Microbiota diversity and anti-Applied and environmental microbiology · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Whole-genome sequence ofMicrobiology resource announcements · 2023
    Article
  19. Assessing the threat of bat-associated fungal pathogens.One health (Amsterdam, Netherlands) · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Zhongle LiCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, 130018, China.
Aoqiang LiJilin Provincial Key Laboratory of Animal Resource Conservation and Utilization, Northeast Normal University, 2555 Jingyue Street, Changchun, 130117, China.
Joseph R HoytDepartment of Biological Sciences, Virginia Polytechnic Institute, Blacksburg, VA, 24060, USA.
Wentao DaiJilin Provincial Key Laboratory of Animal Resource Conservation and Utilization, Northeast Normal University, 2555 Jingyue Street, Changchun, 130117, China.
Haixia LengJilin Provincial Key Laboratory of Animal Resource Conservation and Utilization, Northeast Normal University, 2555 Jingyue Street, Changchun, 130117, China.
Yanfei LiCollege of Chinese Medicine Materials, Jilin Agricultural University, Changchun, 130118, China.
Wei LiCollege of Chinese Medicine Materials, Jilin Agricultural University, Changchun, 130118, China.
Sen LiuInstitute of Resources and Environment, Henan Polytechnic University, Jiaozuo, 454000, China.
Longru JinJilin Provincial Key Laboratory of Animal Resource Conservation and Utilization, Northeast Normal University, 2555 Jingyue Street, Changchun, 130117, China.
Keping SunJilin Provincial Key Laboratory of Animal Resource Conservation and Utilization, Northeast Normal University, 2555 Jingyue Street, Changchun, 130117, China.ORCID 0000-0002-4227-9818
Jiang FengCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, 130018, China.
Northeast Normal University · CNJilin Agricultural University · CNMinistry of Education of the People's Republic of China · CNHenan Polytechnic University · CNVirginia Tech · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

White-nose syndrome, a disease that is caused by the psychrophilic fungus Pseudogymnoascus destructans, has threatened several North America bat species with extinction. Recent studies have shown that East Asian bats are infected with P. destructans but show greatly reduced infections. While several factors have been found to contribute to these reduced infections, the role of specific microbes in limiting P. destructans growth remains unexplored. We isolated three bacterial strains with the ability to inhibit P. destructans, namely, Pseudomonas yamanorum GZD14026, Pseudomonas brenneri XRD11711 and Pseudomonas fragi GZD14479, from bats in China. Pseudomonas yamanorum, with the highest inhibition score, was selected to extract antifungal active substance. Combining mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy analyses, we identified the active compound inhibiting P. destructans as phenazine-1-carboxylic acid (PCA), and the minimal inhibitory concentration (MIC) was 50.12 μg ml

Indexed as

AscomycotaChiropteraAnimalsBacteriaPseudomonas

Identifiers

PMID33559264
PMCPMC8867990
OpenAlexW3128140871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.