Evidence map›Paper›PMID 33559016›Full record

ArticleJournal of autism and developmental disorders2021

A Longitudinal Study of Language Trajectories and Treatment Outcomes of Early Intensive Behavioral Intervention for Autism.

Thomas W Frazier, Eric W Klingemier, Christa J Anderson, Grace W Gengoux, Eric A Youngstrom, Antonio Y Hardan

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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  11. Proportion and Profile of Autistic Children Not Acquiring Spoken Language Despite Receiving Evidence-Based Early Interventions.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2025
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  20. Trajectory research in children with an autism diagnosis: A scoping review.Autism : the international journal of research and practice · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Thomas W FrazierCenter for Autism and Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, USA. tfrazier@jcu.edu.ORCID http://orcid.org/0000-0002-6951-2667
Eric W KlingemierCenter for Autism and Caregiver Experience, Cleveland Clinic, Cleveland, OH, USA.
Christa J AndersonDepartment of Health Psychology, University of Missouri, Columbia, MO, USA.
Grace W GengouxDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Eric A YoungstromDepartments of Psychology and Neuroscience and Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Antonio Y HardanDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stanford University · USAutism Speaks · USCleveland Clinic · USUniversity of Missouri Health System · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study examined language trajectories and placement outcomes for children with autism spectrum disorder (ASD) receiving early intensive behavioral intervention (EIBI). Language measures were collected at baseline and 6, 12, 18, 24, and 36 months or until exit from EIBI in 131 children with ASD. Growth models estimated overall and subgroup language trajectories. Overall, children receiving EIBI showed substantial increases in language relative to normative expectations. Earlier age at EIBI start, higher baseline cognitive function, and lower baseline ASD severity predicted better language trajectories. Although there was significant variability in language trajectories and educational outcomes, most children showed significant increases in language scores, relative to normative expectations. Additional research, in more representative samples, is needed to understand this variability.

Indexed as

Autism Spectrum DisorderAutistic DisorderChildHumansLanguageLongitudinal StudiesTreatment OutcomeApplied behavior analysisEducationGrowth modelLanguageOutcomesPrediction

Identifiers

PMID33559016
OpenAlexW3126988193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.