Evidence map›Paper›PMID 33559004›Full record

ArticleSleep & breathing = Schlaf & Atmung2021

Machine learning for image-based detection of patients with obstructive sleep apnea: an exploratory study.

Satoru Tsuiki, Takuya Nagaoka, Tatsuya Fukuda, Yuki Sakamoto, Fernanda R Almeida, Hideaki Nakayama, Yuichi Inoue, Hiroki Enno

Open access · hybridAbstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

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  16. Automated deep neural network analysis of lateral cephalogram data can aid in detecting obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Satoru TsuikiInstitute of Neuropsychiatry, 91, Bentencho, Shinjuku-ku, Tokyo, 162-0851, Japan. strtsuiki@gmail.com.
Takuya NagaokaRist Inc., Kyoto, Japan.
Tatsuya FukudaInstitute of Neuropsychiatry, 91, Bentencho, Shinjuku-ku, Tokyo, 162-0851, Japan.
Yuki SakamotoRist Inc., Kyoto, Japan.
Fernanda R AlmeidaDepartment of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, Vancouver, Canada.
Hideaki NakayamaInstitute of Neuropsychiatry, 91, Bentencho, Shinjuku-ku, Tokyo, 162-0851, Japan.
Yuichi InoueInstitute of Neuropsychiatry, 91, Bentencho, Shinjuku-ku, Tokyo, 162-0851, Japan.
Hiroki EnnoRist Inc., Kyoto, Japan.
Research Organization for Information Science and Technology · JPSleep Comprehensive Care Clinic Yoyogi · JPTokyo Medical University · JPUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn 2-dimensional lateral cephalometric radiographs, patients with severe obstructive sleep apnea (OSA) exhibit a more crowded oropharynx in comparison with non-OSA. We tested the hypothesis that machine learning, an application of artificial intelligence (AI), could be used to detect patients with severe OSA based on 2-dimensional images.

methodsA deep convolutional neural network was developed (n = 1258; 90%) and tested (n = 131; 10%) using data from 1389 (100%) lateral cephalometric radiographs obtained from individuals diagnosed with severe OSA (n = 867; apnea hypopnea index > 30 events/h sleep) or non-OSA (n = 522; apnea hypopnea index < 5 events/h sleep) at a single center for sleep disorders. Three kinds of data sets were prepared by changing the area of interest using a single image: the original image without any modification (full image), an image containing a facial profile, upper airway, and craniofacial soft/hard tissues (main region), and an image containing part of the occipital region (head only). A radiologist also performed a conventional manual cephalometric analysis of the full image for comparison.

resultsThe sensitivity/specificity was 0.87/0.82 for full image, 0.88/0.75 for main region, 0.71/0.63 for head only, and 0.54/0.80 for the manual analysis. The area under the receiver-operating characteristic curve was the highest for main region 0.92, for full image 0.89, for head only 0.70, and for manual cephalometric analysis 0.75.

conclusionsA deep convolutional neural network identified individuals with severe OSA with high accuracy. Future research on this concept using AI and images can be further encouraged when discussing triage of OSA.

Indexed as

CephalometryDeep LearningRadiographyAdultFemaleHumansMaleMiddle AgedSensitivity and SpecificitySleep Apnea, ObstructiveArtificial intelligenceMachine learningObstructive sleep apneaOropharyngeal crowding

Identifiers

PMID33559004
PMCPMC8590647
OpenAlexW3127252284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.