Evidence map›Paper›PMID 33558853›Full record

ArticleKidney international reports2021

Decreasing Incidence of Acute Kidney Injury in Patients with COVID-19 Critical Illness in New York City.

David M Charytan, Sam Parnia, Minesh Khatri, Christopher M Petrilli, Simon Jones, Judith Benstein, Leora I Horwitz

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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  12. Long-term interplay between COVID-19 and chronic kidney disease.International urology and nephrology · 2023
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  19. [Acute kidney injury and COVID-19: lung-kidney crosstalk during severe inflammation].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David M CharytanDepartment of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Sam ParniaDepartment of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Minesh KhatriNew York University Winthrop School of Medicine, Mineola, New York, USA.
Christopher M PetrilliDepartment of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Simon JonesDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Judith BensteinDepartment of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Leora I HorwitzDepartment of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
New York University · USWinthrop-University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionReports from the United States suggest that acute kidney injury (AKI) frequently complicates coronavirus disease 2019 (COVID-19), but understanding of AKI risks and outcomes is incomplete. In addition, whether kidney outcomes have evolved during the course of the pandemic is unknown.

methodsWe used electronic medical records to identify patients with COVID-19 with and without AKI admitted to 3 New York Hospitals between March 2 and August 25, 2020. Outcomes included AKI overall and according to admission week, AKI stage, the requirement for new renal replacement therapy (RRT), mortality, and recovery of kidney function. Logistic regression was used to assess associations of patient characteristics and outcomes.

resultsOf 4732 admissions, 1386 (29.3%) patients had AKI. Among those with AKI, 717 (51.7%) had stage 1 disease, 132 (9.5%) had stage 2 disease, 537 (38.7%) had stage 3 disease, and 237 (17.1%) required RRT initiation. In March, 536 of 1648 (32.5%) patients developed AKI compared with 15 of 87 (17.2%) in August (

conclusionsAKI impacts a high proportion of admitted patients with COVID-19 and is associated with high mortality, particularly when RRT is required. AKI incidence appears to be decreasing over time and kidney function frequently recovers in those who survive.

Indexed as

acute renal failureCOVID-19critical illnessmortalityrenal replacement therapySARS-CoV-2

Identifiers

PMID33558853
PMCPMC7857986
OpenAlexW3128982224

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.