ArticleNature ecology & evolution2021
Metabolomic signatures of coral bleaching history.
Article in Nature ecology & evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 112 citations in OpenAlex.
- Environmental drivers of metabolomic profiles within and between cryptic lineages of Montastraea cavernosa, the great star coral.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Seasonal Physiological Strategies Reveal Contrasting Host-Symbiont Dynamics Among Dominant Indo-Pacific Reef-Building Corals.Ecology and evolution · 2026Article
- Extracellular electron transfer by the cultured coral photosymbiont Symbiodinium microadriaticum.Photosynthesis research · 2026Article
- Transcriptional responses of reef-building coral Leptoria phrygia to localized thermal anomalies: a seasonal and experimental approach.Scientific reports · 2026Article
- Oxylipin-mediated metabolic signatures of symbiosis homeostasis and thermal stress in a model sea anemone.The ISME journal · 2026Article
- Heat stress reproportions distinct metabolic sub-populations of coral-algal endosymbionts.ISME communications · 2026Article
- Brine Shrimp Feeding Contributes to Fast Growth and Enhanced Immune Capacity of Reattached Polyps of Scleractinian CoralAnimals : an open access journal from MDPI · 2025Article
- Octadecanoids as emerging lipid mediators in cnidarian-dinoflagellate symbiosis.Communications biology · 2025Article
- Species-specific retention vs. recovery of coral thermal tolerance following nursery propagation.Communications biology · 2025Article
- Intergenerational metabolomic signatures of bleaching resistance in corals.Nature communications · 2025Article
- Article
- Spatially restricted coral bleaching as an ecological manifestation of within-colony heterogeneity.Communications biology · 2025Review
- Lipidomic and physiological changes in the coral Acropora aspera during bleaching and recovery.Scientific reports · 2025Article
- Heat-induced stress modulates cell surface glycans and membrane lipids of coral symbionts.The ISME journal · 2025Article
- Extreme Events Contributing to Tipping Elements and Tipping Points.Surveys in geophysics · 2025Review
- Article
- Article
- Metabolomic profiles of stony coral species from the Dry Tortugas National Park display inter- and intraspecies variation.mSystems · 2024Article
- Saving coral reefs: significance and biotechnological approaches for coral conservation.Advanced biotechnology · 2024Review
- Unlocking the genomic potential of Red Sea coral probiotics.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coral bleaching has a profound impact on the health and function of reef ecosystems, but the metabolomic effects of coral bleaching are largely uncharacterized. Here, untargeted metabolomics was used to analyse pairs of adjacent Montipora capitata corals that had contrasting bleaching phenotypes during a severe bleaching event in 2015. When these same corals were sampled four years later while visually healthy, there was a strong metabolomic signature of bleaching history. This was primarily driven by betaine lipids from the symbiont, where corals that did not bleach were enriched in saturated lyso-betaine lipids. Immune modulator molecules were also altered by bleaching history in both the coral host and the algal symbiont, suggesting a shared role in partner choice and bleaching response. Metabolomics from a separate set of validation corals was able to predict the bleaching phenotype with 100% accuracy. Experimental temperature stress induced phenotype-specific responses, which magnified differences between historical bleaching phenotypes. These findings indicate that natural bleaching susceptibility is manifested in the biochemistry of both the coral animal and its algal symbiont. This metabolome difference is stable through time and results in different physiological responses to temperature stress. This work provides insight into the biochemical mechanisms of coral bleaching and presents a valuable new tool for resilience-based reef restoration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.