ArticleThe ISME journal2021
The occurrence and ecology of microbial chain elongation of carboxylates in soils.
Article in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Environmental considerations and bioremediation applications of the metal-, nitrate-, and organohalide-respiring bacteriumApplied and environmental microbiology · 2026Review
- Acetate to caproate: metagenomic insights into functional shifts in a methane-arrested anaerobic bioreactor.FEMS microbes · 2026Article
- Evaluation of lab-defined syngas and acetate as substrates for HApplied microbiology and biotechnology · 2025Article
- Bioturbation analysis of microbial community and organic acid metabolism in the enriched liquid of pit mud by Daqu, HuangShui, and ZaoPei.Food science and biotechnology · 2025Article
- Enhancing Gas Fermentation Efficiency via Bioaugmentation withBioengineering (Basel, Switzerland) · 2025Article
- Aromatic pollutants rewire soil microbial carbon fixation via chain elongation.The ISME journal · 2025Article
- Metabolic diversity and responses of anteater clostridial isolates to chitin-based substrates.Frontiers in veterinary science · 2025Article
- Acetate Shock Loads Enhance CO Uptake Rates of Anaerobic Microbiomes.Microbial biotechnology · 2024Article
- Identification of volatile metabolites produced from levodopa metabolism by different bacteria strains of the gut microbiome.BMC microbiology · 2024Article
- Acetylene Tunes Microbial Growth During Aerobic Cometabolism of Trichloroethene.Environmental science & technology · 2024Article
- Article
- High Efficacy Two-Stage Metal Treatment Incorporating Basic Oxygen Furnace Slag and Microbiological Sulfate Reduction.ACS ES&T engineering · 2024Article
- Wetlands harbor lactic acid-driven chain elongators.Microbiology spectrum · 2024Article
- Physiological and stoichiometric characterization of ethanol-based chain elongation in the absence of short-chain carboxylic acids.Scientific reports · 2023Article
- Formate-induced CO tolerance and methanogenesis inhibition in fermentation of syngas and plant biomass for carboxylate production.Biotechnology for biofuels and bioproducts · 2023Article
- Mixotrophic chain elongation with syngas and lactate as electron donors.Microbial biotechnology · 2023Article
- Butanol as a major product during ethanol and acetate chain elongation.Frontiers in bioengineering and biotechnology · 2023Article
- Adaptability of a Caproate-Producing Bacterium Contributes to Its Dominance in an Anaerobic Fermentation System.Applied and environmental microbiology · 2021Article
- An Ion Chromatography Method for Simultaneous Quantification of Chromate, Arsenate, Selenate, Perchlorate, and Other Inorganic Anions in Environmental Media.Environmental engineering science · 2021Article
- Effect of Oxygen Contamination on Propionate and Caproate Formation in Anaerobic Fermentation.Frontiers in bioengineering and biotechnology · 2021Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chain elongation is a growth-dependent anaerobic metabolism that combines acetate and ethanol into butyrate, hexanoate, and octanoate. While the model microorganism for chain elongation, Clostridium kluyveri, was isolated from a saturated soil sample in the 1940s, chain elongation has remained unexplored in soil environments. During soil fermentative events, simple carboxylates and alcohols can transiently accumulate up to low mM concentrations, suggesting in situ possibility of microbial chain elongation. Here, we examined the occurrence and microbial ecology of chain elongation in four soil types in microcosms and enrichments amended with chain elongation substrates. All soils showed evidence of chain elongation activity with several days of incubation at high (100 mM) and environmentally relevant (2.5 mM) concentrations of acetate and ethanol. Three soils showed substantial activity in soil microcosms with high substrate concentrations, converting 58% or more of the added carbon as acetate and ethanol to butyrate, butanol, and hexanoate. Semi-batch enrichment yielded hexanoate and octanoate as the most elongated products and microbial communities predominated by C. kluyveri and other Firmicutes genera not known to undergo chain elongation. Collectively, these results strongly suggest a niche for chain elongation in anaerobic soils that should not be overlooked in soil microbial ecology studies.
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