ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2022
An examination of the relationships between attention/deficit hyperactivity disorder symptoms and functional connectivity over time.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Longitudinal MRI studies of children with attention-deficit/hyperactivity disorder: A systematic review.Psychiatry and clinical neurosciences · 2026Pooled it
- A connectome-based neural correlate of pediatric ADHD hyperactivity-impulsivity symptoms.Frontiers in psychiatry · 2026Article
- Real-world goal-directed behavior reveals aberrant functional brain connectivity in children with ADHD.PloS one · 2025Article
- Distinct structural brain network properties in children with familial versus non-familial attention-deficit/hyperactivity disorder (ADHD).Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Attention-deficit/hyperactivity disorder.Nature reviews. Disease primers · 2024Review
- Delayed Outgrowth in Response to the BDNF and Altered Synaptic Proteins in Neurons From SHR Rats.Neurochemical research · 2023Article
- Cortical structural and functional coupling during development and implications for attention deficit hyperactivity disorder.Translational psychiatry · 2023Article
- Longitudinal trajectories of childhood and adolescent attention deficit hyperactivity disorder diagnoses in three cohorts.EClinicalMedicine · 2023Article
- Evidence from "big data" for the default-mode hypothesis of ADHD: a mega-analysis of multiple large samples.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Effects of a single-dose methylphenidate challenge on resting-state functional connectivity in stimulant-treatment naive children and adults with ADHD.Human brain mapping · 2022Article
- ADHD and its neurocognitive substrates: A two sample Mendelian randomization study.Translational psychiatry · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Previous cross-sectional work has demonstrated resting-state connectivity abnormalities in children and adolescents with attention/deficit hyperactivity disorder (ADHD) relative to typically developing controls. However, it is unclear to what extent these neural abnormalities confer risk for later symptoms of the disorder, or represent the downstream effects of symptoms on functional connectivity. Here, we studied 167 children and adolescents (mean age at baseline = 10.74 years (SD = 2.54); mean age at follow-up = 13.3 years (SD = 2.48); 56 females) with varying levels of ADHD symptoms, all of whom underwent resting-state functional magnetic resonance imaging and ADHD symptom assessments on two occasions during development. Resting-state functional connectivity was quantified using eigenvector centrality mapping. Using voxelwise cross-lag modeling, we found that less connectivity at baseline within right inferior frontal gyrus was associated with more follow-up symptoms of inattention (significant at an uncorrected cluster-forming threshold of p ≤ 0.001 and a cluster-level familywise error corrected threshold of p < 0.05). Findings suggest that previously reported cross-sectional abnormalities in functional connectivity within inferior frontal gyrus in patients with ADHD may represent a longitudinal risk factor for the disorder, in line with efforts to target this region with novel therapeutic methods.
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