Evidence map›Paper›PMID 33558517›Full record

ReviewNPJ microgravity2021

Gravity sensing in plant and animal cells.

Ken Takahashi, Hideyuki Takahashi, Takuya Furuichi, Masatsugu Toyota, Makoto Furutani-Seiki, Takeshi Kobayashi, Haruko Watanabe-Takano, Masahiro Shinohara, Takuro Numaga-Tomita, Asako Sakaue-Sawano and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in NPJ microgravity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
10.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Kv2.1 negatively regulates Reissner fiber development.Frontiers in cell and developmental biology · 2025
    Article
  8. High-resolution, high-throughput analysis ofbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Gravity's effect on biology.Frontiers in physiology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Mechanosensing, from forces to structures.Frontiers in plant science · 2022
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Ken TakahashiDepartment of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan. takah-k2@okayama-u.ac.jp.ORCID http://orcid.org/0000-0002-7580-8691
Hideyuki TakahashiGraduate School of Life Sciences, Tohoku University, Sendai, Japan.
Takuya FuruichiFaculty of Human Life Sciences, Hagoromo University of International Studies, Sakai, Japan.
Masatsugu ToyotaDepartment of Biochemistry and Molecular Biology, Saitama University, Saitama, Japan.ORCID http://orcid.org/0000-0002-9544-0978
Makoto Furutani-SeikiDepartment of Systems Biochemistry in Regeneration and Pathology, Graduate School of Medicine, Yamaguchi University, Yamaguchi, Japan.
Takeshi KobayashiDepartment of Integrative Physiology, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Haruko Watanabe-TakanoDepartment of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan.
Masahiro ShinoharaDepartment of Rehabilitation for the Movement Functions, Research Institute, National Rehabilitation Center for Persons with Disabilities, Tokorozawa, Japan.
Takuro Numaga-TomitaDepartment of Molecular Pharmacology, Shinshu University School of Medicine, Matsumoto, Japan.
Asako Sakaue-SawanoLab for Cell Function and Dynamics, CBS, RIKEN, Wakō, Saitama, Japan.ORCID http://orcid.org/0000-0002-6975-0390
Atsushi MiyawakiLab for Cell Function and Dynamics, CBS, RIKEN, Wakō, Saitama, Japan.
Keiji NaruseDepartment of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.ORCID http://orcid.org/0000-0003-4100-6444
Okayama University · JPRIKEN · JPHagoromo International University · JPNagoya University · JPNational Cerebral and Cardiovascular Center · JPNational Rehabilitation Center for Persons with Disabilities · JPSaitama University · JPShinshu University · JPTohoku University · JPYamaguchi University · JP

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 15H05935MEXT | Japan Society for the Promotion of Science (JSPS) 15H05936
6 · The paper itself

Abstract

Gravity determines shape of body tissue and affects the functions of life, both in plants and animals. The cellular response to gravity is an active process of mechanotransduction. Although plants and animals share some common mechanisms of gravity sensing in spite of their distant phylogenetic origin, each species has its own mechanism to sense and respond to gravity. In this review, we discuss current understanding regarding the mechanisms of cellular gravity sensing in plants and animals. Understanding gravisensing also contributes to life on Earth, e.g., understanding osteoporosis and muscle atrophy. Furthermore, in the current age of Mars exploration, understanding cellular responses to gravity will form the foundation of living in space.

Identifiers

PMID33558517
PMCPMC7870899
OpenAlexW3127595852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.