Evidence map›Paper›PMID 33558449›Full record

ReviewCancers2021

Characterisation of Prostate Lesions Using Transrectal Shear Wave Elastography (SWE) Ultrasound Imaging: A Systematic Review.

Thineskrishna Anbarasan, Cheng Wei, Jeffrey C Bamber, Richard G Barr, Ghulam Nabi

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  9. Review
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  13. [Image-guided biopsy of the prostate gland].Urologie (Heidelberg, Germany) · 2022
    Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Thineskrishna AnbarasanCollege of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh EH8 9YL, UK.ORCID 0000-0003-1049-0093
Cheng WeiAcademic Section of Urology, School of Medicine, University of Dundee, Dundee DD1 4HN, UK.ORCID 0000-0001-5714-4863
Jeffrey C BamberJoint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London SM2 5NG, UK.ORCID 0000-0001-9436-1832
Richard G BarrDepartment of Radiology, Northeastern Ohio Medical University, Rootstown, OH 44272, USA.ORCID 0000-0001-8021-0072
Ghulam NabiAcademic Section of Urology, School of Medicine, University of Dundee, Dundee DD1 4HN, UK.
University of Dundee · GBNortheast Ohio Medical University · USRoyal Marsden NHS Foundation Trust · GBUniversity of Edinburgh · GB

Funding

Cancer Research UK 16464
6 · The paper itself

Abstract

backgroundultrasound-based shear wave elastography (SWE) can non-invasively assess prostate tissue stiffness. This systematic review aims to evaluate SWE for the detection of prostate cancer (PCa) and compare diagnostic estimates between studies reporting the detection of all PCa and clinically significant PCa (csPCa).

methodsa literature search was performed using the MEDLINE, EMBASE, Cochrane Library, ClinicalTrials.gov, and CINAHL databases. Studies evaluating SWE for the detection of PCa using histopathology as reference standard were included.

results16 studies including 2277 patients were included for review. Nine studies evaluated SWE for the detection of PCa using systematic biopsy as a reference standard at the per-sample level, with a pooled sensitivity and specificity of 0.85 (95% CI = 0.74-0.92) and 0.85 (95% CI = 0.75-0.91), respectively. Five studies evaluated SWE for the detection of PCa using histopathology of radical prostatectomy (RP) specimens as the reference standard, with a pooled sensitivity and specificity of 0.71 (95% CI = 0.55-0.83) and 0.74 (95% CI = 0.42-0.92), respectively. Sub-group analysis revealed a higher pooled sensitivity (0.77 vs. 0.62) and specificity (0.84 vs. 0.53) for detection of csPCa compared to all PCa among studies using RP specimens as the reference standard.

conclusionSWE is an attractive imaging modality for the detection of PCa.

Indexed as

prostate cancershear wave elastographyultrasound

Identifiers

PMID33558449
PMCPMC7795187
OpenAlexW3118637508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.