Evidence map›Paper›PMID 33558378›Full record

ArticleBMJ case reports2021

Squamous cell carcinoma at the site of ileo-anal pouch in Crohn's disease.

Dorina Gabriela Condurache, Jonathan P Segal, Ailsa L Hart, Anthony Antoniou

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dorina Gabriela ConduracheGastroenterology, London North West University Healthcare NHS Trust, Harrow, London, UK dorina.condurache@nhs.net.
Jonathan P SegalGastroenterology, London North West University Healthcare NHS Trust, Harrow, London, UK.
Ailsa L HartGastroenterology, St Mark's Hospital and Academic Institute, Harrow, London, UK.
Anthony AntoniouSt Mark's Hospital Foundation, Harrow, London, UK.
London North West Healthcare NHS Trust · GBSt Mark's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few cases of pouch-related cancers have been reported in inflammatory bowel disease, and squamous cell carcinoma (SCC) is very rare. We have reviewed the published literature searching the online databases PubMed and Medline. Since 1979, there have been eight cases of SCC developing after restorative proctocolectomy in ulcerative colitis. To date, there have been no reported cases of SCC of the ileo-anal pouch in Crohn's disease. We present the case of a 59-year-old woman who underwent colectomy with ileal pouch-anal anastomosis for Crohn's disease during the 1990s. The patient was noted to be anaemic and was experiencing significant weight loss with poor pouch function in 2019. Endoscopy with histology and radiological investigation revealed the presence of SCC of the pouch. This was subsequently treated with surgical therapy and chemoradiotherapy.

Indexed as

Carcinoma, Squamous CellChemoradiotherapy, AdjuvantColonic NeoplasmsColonic PouchesCrohn DiseaseFemaleHumansIleostomyMiddle AgedNeoadjuvant TherapyProctocolectomy, RestorativeCrohn's diseaseoncologysurgery

Identifiers

PMID33558378
PMCPMC7872916
OpenAlexW3127989537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.