Evidence map›Paper›PMID 33558327›Full record

ArticleInfection and immunity2021

Purinergic P2X7 Receptor Mediates the Elimination of Trichinella spiralis by Activating NF-κB/NLRP3/IL-1β Pathway in Macrophages.

Fei Guan, Wangfang Jiang, Yang Bai, Xiao Hou, Chunjie Jiang, Chongyang Zhang, Muziazia Lupemba Jacques, Wenqi Liu, Jiahui Lei

Abstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. MALAT1-miR-20b-5p-P2RX7 Axis RegulatesVeterinary sciences · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Vaccines · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Ion channel regulation of gut immunity.The Journal of general physiology · 2023
    Article
  13. Physiologic roles of P2 receptors in leukocytes.Journal of leukocyte biology · 2022
    Review
  14. Article
  15. Review
  16. Article
  17. Protective effect ofFrontiers in cellular and infection microbiology · 2022
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fei GuanDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wangfang JiangDepartment of Clinical Laboratory, Changzhi People's Hospital, Changzhi, China.
Yang BaiDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiao HouDepartment of Clinical Laboratory, General Hospital of Central Theater Command, PLA, Wuhan, China.
Chunjie JiangDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chongyang ZhangDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Muziazia Lupemba JacquesDepartment of Parasitology, School of Basic Medicine, Institute of Medical Technology, Kinshasa, Democratic Republic of the Congo.
Wenqi LiuDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jiahui LeiDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China leijiahui@hotmail.com.ORCID 0000-0002-4223-5663

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichinellosis is one of most neglected foodborne zoonoses worldwide. During

Indexed as

Signal TransductionTrichinella spiralisAnimalsDisease Models, AnimalGene ExpressionInterleukin-1betaIntestinal MucosaMacrophagesMiceMice, KnockoutNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinParasite LoadPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X7TrichinellosisInterleukin-1betaNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X7IL-1βmacrophagesNF-κBNLPR3P2X7RTrichinella spiralis

Identifiers

PMID33558327
PMCPMC8091101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.