Evidence map›Paper›PMID 33558323›Full record

ReviewInfection and immunity2021

Finding Order in the Chaos: Outstanding Questions in Klebsiella pneumoniae Pathogenesis.

Shekina Gonzalez-Ferrer, Hernán F Peñaloza, James A Budnick, William G Bain, Hayley R Nordstrom, Janet S Lee, Daria Van Tyne

Open access · greenAbstract readReview
In one paragraph

Review in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.

  1. Pooled it
  2. Article
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  6. Article
  7. TARGETING THE CAPSULE OFbioRxiv : the preprint server for biology · 2026
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  8. Article
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  12. Differential virulence potential of different clades of multidrug-resistantmedRxiv : the preprint server for health sciences · 2026
    Article
  13. Review
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  17. The acquisition ofmBio · 2026
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  18. Targeting the capsule ofFrontiers in immunology · 2026
    Article
  19. Factors associated withSouthern African journal of infectious diseases · 2026
    Article
  20. Article

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shekina Gonzalez-FerrerAcute Lung Injury Center of Excellence, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-0188-8844
Hernán F PeñalozaAcute Lung Injury Center of Excellence, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-1593-678X
James A BudnickDivision of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9867-4895
William G BainAcute Lung Injury Center of Excellence, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-8506-0552
Hayley R NordstromDivision of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Janet S LeeAcute Lung Injury Center of Excellence, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-6812-6043
Daria Van TyneDivision of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA vantyne@pitt.edu.ORCID 0000-0001-7284-0103
University of Pittsburgh · US

Funding

Regulation of Cardiolin Byosynthesis in Epithelial InjuryP01HL114453 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MALLAMPALLI, RAMA K · 2014 to 2023
$21.3M
Mechanisms of host protection against pathogen-secreted proteases in acute lung injuryR01HL136143 · NHLBI · WASHINGTON UNIVERSITY · PI LEE, JANET SOJUNG · 2017 to 2024
$4.4M
The role of ACOD1 in immunomodulation in intrapulmonary Klebsiella pneumoniae infectionR01HL142084 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHEN, KONG · 2018 to 2021
$2.4M
University of Pittsburgh Training Program in Antimicrobial ResistanceT32AI138954 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRISON, LEE H · 2019 to 2023
$971k
Bacterial Evasion of Innate Defenses at the Ocular SurfaceR00EY028222 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VAN TYNE, DARIA N · 2018 to 2020
$728k
Patient-Oriented Research in Acute Lung Injury and Host Defense in the ICUK24HL143285 · NHLBI · WASHINGTON UNIVERSITY · PI LEE, JANET SOJUNG · 2019 to 2023
$579k
Evaluation of alternative complement activity within an ARDS cohortR21HL148088 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NOURAIE, SEYED MEHDI · 2020 to 2021
$248k
Platelet factors attenuate alveolar injury during severe pneumoniaIK2BX004886 · VA · VETERANS HEALTH ADMINISTRATION · PI BAIN, WILLIAM G · 2020 to 2024
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BLRD VA IK2 BX004886NEI NIH HHS R00 EY028222NHLBI NIH HHS K24 HL143285NHLBI NIH HHS P01 HL114453NHLBI NIH HHS R01 HL136143NHLBI NIH HHS R01 HL142084NIAID NIH HHS T32 AI138954
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease SusceptibilityAnimalsGeography, MedicalGlobal HealthHost-Pathogen InteractionsHumansImmunity, InnateKlebsiella InfectionsKlebsiella pneumoniaePopulation SurveillanceVirulenceevolutioninnate immune systemKlebsiellapathogenesis

Identifiers

PMID33558323
PMCPMC8090965
OpenAlexW3128743052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.