ArticleInfection and immunity2021
Contribution of Noncanonical Antigens to Virulence and Adaptive Immunity in Human Infection with Enterotoxigenic E. coli.
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In one paragraph
Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 27 citations in OpenAlex.
- Review
- Systemic and mucosal immunity to enterotoxigenicFrontiers in immunology · 2026Review
- EatA mediated degradation of intestinal mucus is species-specific and driven by MUC2 structural features.Nature communications · 2025Article
- MecVax, an Epitope- and Structure-Based Broadly Protective Subunit Vaccine Against EnterotoxigenicMicroorganisms · 2025Review
- Recent progress in enterotoxigenicInfection and immunity · 2025Review
- An Asset for Food Safety: The Knowledge Behind the Physiological Alterations Induced by ETEC Enterotoxins.Foods (Basel, Switzerland) · 2025Review
- Genomic insights into a diarrheal outbreak in Bangladesh reveal novel ETEC lineages and expansion of CS23 colonization factor.Microbiology spectrum · 2025Article
- Parenteral vaccination with recombinant EtpA glycoprotein impairs enterotoxigenicInfection and immunity · 2025Article
- RecombinantApplied and environmental microbiology · 2025Article
- Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin.PLoS pathogens · 2024Article
- Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenicbioRxiv : the preprint server for biology · 2024Article
- A First in Human Clinical Trial Assessing the Safety and Immunogenicity of Two Intradermally Delivered EnterotoxigenicMicroorganisms · 2023Article
- The role of the minor colonization factor CS14 in adherence to intestinal cell models by geographically diverse ETEC isolates.mSphere · 2023Article
- Seroprevalence Study of Conserved EnterotoxigenicMicroorganisms · 2023Article
- Prevalence of diarrheagenic Escherichia coli and impact on child health in Cap-Haitien, Haiti.PLOS global public health · 2023Article
- Genomics and pathotypes of the many faces of Escherichia coli.FEMS microbiology reviews · 2022Article
- The role of CFA/I in adherence and toxin delivery by ETEC expressing multiple colonization factors in the human enteroid model.PLoS neglected tropical diseases · 2022Article
- EnterotoxigenicInfection and immunity · 2022Article
- Emerging Themes in the Molecular Pathogenesis of Enterotoxigenic Escherichia coli.The Journal of infectious diseases · 2021Article
- Vaccines for Protecting Infants from Bacterial Causes of Diarrheal Disease.Microorganisms · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 2 countries.
F M KuhlmannDepartment of Internal Medicine, Division of Infectious Diseases, Washington University, St. Louis, Missouri, USA.ORCID 0000-0003-1085-0589
R O LaineDepartment of Internal Medicine, Division of Infectious Diseases, Washington University, St. Louis, Missouri, USA.
S AfrinDepartment of Internal Medicine, Division of Infectious Diseases, Washington University, St. Louis, Missouri, USA.
R NakajimaVaccine R&D Center, University of California, Irvine, Irvine, California, USA.ORCID 0000-0002-6026-3342
M AkhtarInfectious Diseases Division, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
T VickersDepartment of Internal Medicine, Division of Infectious Diseases, Washington University, St. Louis, Missouri, USA.
K ParkerDepartment of Internal Medicine, Division of Infectious Diseases, Washington University, St. Louis, Missouri, USA.
N N NizamInfectious Diseases Division, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
V GriguraDepartment of Internal Medicine, Division of Infectious Diseases, Washington University, St. Louis, Missouri, USA.
C W GossDivision of Biostatistics, Washington University, St. Louis, Missouri, USA.
P L FelgnerVaccine R&D Center, University of California, Irvine, Irvine, California, USA.
D A RaskoDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-7337-7154
F QadriInfectious Diseases Division, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0002-8928-9888
J M FleckensteinDepartment of Internal Medicine, Division of Infectious Diseases, Washington University, St. Louis, Missouri, USA jfleckenstein@wustl.edu.ORCID 0000-0002-1148-697X
Washington University in St. Louis · USInternational Centre for Diarrhoeal Disease Research · BDUniversity of California, Irvine · USUniversity of Maryland, Baltimore · US
Funding
Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RASKO, DAVID A · 2014 to 2023
$36.5MNovel Antigen Identification for an Enterotoxigenic E. coli VaccineR01AI089894 · NIAID · WASHINGTON UNIVERSITY · PI Zachary T. Berndsen, James Michael Fleckenstein · 2010 to 2026
$7.4MMolecular Microbiology of Enterotoxigenic E. coli Pathogen-Host InteractionsR01AI126887 · NIAID · WASHINGTON UNIVERSITY · PI FLECKENSTEIN, JAMES MICHAEL · 2016 to 2020
$1.6MMolecular Pathogenesis of Enterotoxigenic Escherichia coli InfectionsI01BX004825 · VA · ST. LOUIS VA MEDICAL CENTER · PI FLECKENSTEIN, JAMES MICHAEL · 2020 to 2024
–BLRD VA I01 BX004825NIAID NIH HHS R01 AI089894NIAID NIH HHS R01 AI126887NIAID NIH HHS U19 AI110820
Abstract
Enterotoxigenic
Indexed as
Adaptive ImmunityAdhesins, BacterialAntigens, BacterialDisease SusceptibilityEnterotoxigenic Escherichia coliEscherichia coli InfectionsEscherichia coli ProteinsHost-Pathogen InteractionsHumansVirulenceVirulence FactorsAdhesins, BacterialAntigens, BacterialEscherichia coli ProteinsVirulence Factorsdiarrheaenteric pathogenspathogenesissurface antigensvaccines
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.