Evidence map›Paper›PMID 33558234›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1.

Peng Zhang, Alexia J Katzaroff, Laura A Buttitta, Yiqin Ma, Huaqi Jiang, Derek W Nickerson, Jan Inge Øvrebø, Bruce A Edgar

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Yun/Prohibitin complex regulates adultProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Peng ZhangHuntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112.ORCID 0000-0002-0773-2904
Alexia J KatzaroffMolecular and Cellular Biology Program, University of Washington, Seattle, WA 98195.
Laura A ButtittaDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.ORCID 0000-0002-5064-0650
Yiqin MaHuntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112.
Huaqi JiangDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
Derek W NickersonDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
Jan Inge ØvrebøHuntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112.
Bruce A EdgarHuntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112; bruce.edgar@hci.utah.edu.ORCID 0000-0002-3383-2044
University of Utah · USFred Hutch Cancer Center · USUniversity of Washington · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KATHARINE S ULLMAN · 1986 to 2026
$72.6M
INTERDISCIPLINARY TRAINING IN DEVELOPMENTAL BIOLOGYT32HD007183 · NICHD · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 1985 to 2015
$5.7M
Growth Regulation during Drosophila DevelopmentR01GM051186 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ROHRSCHNEIDER, LARRY RAY · 1994 to 2011
$5.2M
Damage Sensing and Growth Control in the Drosophila GutR01GM124434 · NIGMS · UNIVERSITY OF UTAH · PI EDGAR, BRUCE ALEXANDER · 2017 to 2020
$1.7M
Chromatin remodeling at cell cycle exitR01GM127367 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BUTTITTA, LAURA A · 2018 to 2022
$1.6M
Translational Control of Cell ProliferationR01GM126033 · NIGMS · UNIVERSITY OF UTAH · PI EDGAR, BRUCE ALEXANDER · 2018 to 2020
$1.3M
Developmental control of cell cycle exitR01GM070887 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BREEDEN, LINDA L. · 2006 to 2009
$1.1M
Mechanisms controlling cell cycle exit upon terminal differentiationR00GM086517 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BUTTITTA, LAURA A · 2011 to 2013
$710k
Mechanisms controlling cell cycle exit upon terminal differentiationK99GM086517 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BUTTITTA, LAURA A · 2009 to 2010
$180k
NCI NIH HHS P30 CA042014NICHD NIH HHS T32 HD007183NIGMS NIH HHS K99 GM086517NIGMS NIH HHS R00 GM086517NIGMS NIH HHS R01 GM051186NIGMS NIH HHS R01 GM070887NIGMS NIH HHS R01 GM124434NIGMS NIH HHS R01 GM126033NIGMS NIH HHS R01 GM127367
6 · The paper itself

Abstract

Using a gain-of-function screen in

Indexed as

AnimalsCell CycleCompound Eye, ArthropodDrosophila melanogasterDrosophila ProteinsE2F1 Transcription FactorGain of Function MutationGenetic Complementation TestIntestinal MucosaTranscription FactorsCbt protein, DrosophilaDrosophila ProteinsE2F1 Transcription FactorTranscription FactorsCabut (Cbt)cell cycle exitE2F1intestinal stem cell (ISC)proliferation

Identifiers

PMID33558234
PMCPMC7896318
OpenAlexW3127438551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.