Observational studyCritical care (London, England)2021
Static compliance of the respiratory system in COVID-19 related ARDS: an international multicenter study.
Observational study in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Respiratory system mechanics, gas exchange, and outcomes in mechanically ventilated patients with COVID-19-related acute respiratory distress syndrome: a systematic review and meta-analysis.The Lancet. Respiratory medicine · 2022Pooled it
- Implications of Lung Compliance Phenotypes in COVID-19-Induced Acute Respiratory Distress Syndrome.Cureus · 2026Article
- A Comparative Analysis of Early Ventilator Mechanics in COVID-19 vs. Non-COVID-19 ARDS: A Single-Center ED-Based Cohort Study.Healthcare (Basel, Switzerland) · 2025Article
- The Effect of Prone Position on Right Ventricular Functions in CARDS: Is Survival Predictable when Evaluated Through Transesophageal Echocardiography?Turkish journal of anaesthesiology and reanimation · 2025Article
- Comparing the impact of targeting limited driving pressure to low tidal volume ventilation on mortality in mechanically ventilated adults with COVID-19 ARDS: an exploratory target trial emulation.BMJ open respiratory research · 2024Article
- Predictive value of invasive mechanical ventilation parameters for mortality in COVID-19 related ARDS: a retrospective cohort study.Scientific reports · 2024Observational
- Oscillometry Longitudinal Data on COVID-19 Acute Respiratory Syndrome Treated with Non-Invasive Respiratory Support.Journal of clinical medicine · 2024Article
- Driving pressure, as opposed to tidal volume based on predicted body weight, is associated with mortality: results from a prospective cohort of COVID-19 acute respiratory distress syndrome patients.Critical care science · 2024Observational
- Development and evaluation of a mechanical ventilator-sharing system.Frontiers in medicine · 2024Article
- A bibliometric analysis of respiratory mechanics research related to acute respiratory distress syndrome from 1985 to 2023.Frontiers in medicine · 2024Article
- Physiologic Markers of Disease Severity in ARDS.Respiratory care · 2023Review
- Response to Prone Position in COVID-19 and Non-COVID-19 Patients with Severe ARDS Supported by vvECMO.Journal of clinical medicine · 2023Article
- Pathophysiology of Hypoxemia in COVID-19 Lung Disease.Clinics in chest medicine · 2023Review
- Barotrauma in COVID-19 acute respiratory distress syndrome: retrospective analysis of the COVADIS prospective multicenter observational database.BMC anesthesiology · 2023Observational
- Outcomes Among Mechanically Ventilated Patients With Severe Pneumonia and Acute Hypoxemic Respiratory Failure From SARS-CoV-2 and Other Etiologies.JAMA network open · 2023Article
- Ventilatory Parameters Measured After One Week of Mechanical Ventilation and Survival in COVID-19-Related ARDS.Respiratory care · 2023Article
- Programmed multi-level ventilation in COVID-19-related acute respiratory distress syndrome: a multi-center retrospective observational study.The Journal of international medical research · 2022Observational
- External chest-wall compression in prolonged COVID-19 ARDS with low-compliance: a physiological study.Annals of intensive care · 2022Article
- Myocardial performance index increases at long-term follow-up in patients with mild to moderate COVID-19.Echocardiography (Mount Kisco, N.Y.) · 2022Article
- From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?Translational research : the journal of laboratory and clinical medicine · 2022Review
Corrections and comments
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Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundControversies exist on the nature of COVID-19 related acute respiratory distress syndrome (ARDS) in particular on the static compliance of the respiratory system (Crs). We aimed to analyze the association of Crs with outcome in COVID-19-associated ARDS, to ascertain its determinants and to describe its evolution at day-14.
methodsIn this observational multicenter cohort of patients with moderate to severe Covid-19 ARDS, Crs was measured at day-1 and day-14. Association between Crs or Crs/ideal body weight (IBW) and breathing without assistance at day-28 was analyzed with multivariable logistic regression. Determinants were ascertained by multivariable linear regression. Day-14 Crs was compared to day-1 Crs with paired t-test in patients still under controlled mechanical ventilation.
resultsThe mean Crs in 372 patients was 37.6 ± 13 mL/cmH
conclusionIn a large multicenter cohort of moderate to severe COVID-19 ARDS, mean Crs was decreased below 40 mL/cmH
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