Evidence map›Paper›PMID 33557808›Full record

ArticleBMC musculoskeletal disorders2021

Gravity determines the direction of nerve roots sedimentation in the lumbar spinal canal.

Jun Yang, Zhiyun Feng, Nian Chen, Zhenhua Hong, Yongyu Zheng, Jiang Yang, Tingjie Zhou, Xin Yao, Taifeng Xu, Linting Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Use and misuse of the sedimentation sign in lumbar spine stenosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jun YangDepartment of Orthopedic Surgery, Sanmen People's Hospital, Taizhou, China.
Zhiyun FengDepartment of Orthopedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. fengzhiyun@zju.edu.cn.ORCID http://orcid.org/0000-0003-1995-2952
Nian ChenDepartment of Orthopedic Surgery, Sanmen People's Hospital, Taizhou, China.
Zhenhua HongDepartment of Orthopedic Surgery, Taizhou Hospital, Taizhou, China.
Yongyu ZhengDepartment of Orthopedic Surgery, Sanmen People's Hospital, Taizhou, China.
Jiang YangDepartment of Orthopedic Surgery, Sanmen People's Hospital, Taizhou, China.
Tingjie ZhouDepartment of Orthopedic Surgery, Sanmen People's Hospital, Taizhou, China.
Xin YaoDepartment of Orthopedic Surgery, Sanmen People's Hospital, Taizhou, China.
Taifeng XuDepartment of Orthopedic Surgery, Sanmen People's Hospital, Taizhou, China.
Linting ZhangOperating room, Sanmen People's Hospital, Taizhou, China. 2337825016@qq.com.
Nantong University · CNFirst Affiliated Hospital Zhejiang University · CNWenzhou Medical University · CN

Funding

Medicine and health science and technology plan in Zhejiang province 2020RC058Public Welfare Program of Science and Technology Department of Zhejiang Province LGF19H060012Technology Bureau of Sammen 16306Technology Bureau of Sammen 18306Technology Program of Traditional Chinese Medicine Department of Zhejiang Province 2017ZZ011
6 · The paper itself

Abstract

objectivesTo investigate the role of gravity in the sedimentation of lumbar spine nerve roots using magnetic resonance (MR) imaging of various body positions.

methodsA total of 56 patients, who suffered from back pain and underwent conventional supine lumbar spine MR imaging, were selected from sanmen hospital database. All the patients were called back to our hospital to perform MR imaging in prone position or lateral position. Furthermore, the sedimentation sign (SedSign) was determined based on the suspension of the nerve roots in the dural sac on cross-sectional MR images, and 31 cases were rated as positive and another 25 cases were negative.

resultsThe mean age of negative SedSign group was significantly younger than that of positive SedSign group (51.7 ± 8.7 vs 68.4 ± 10.5, P < 0.05). The constitutions of clinical diagnosis were significantly different between patients with a positive SedSign and those with a negative SedSign (P < 0.001). Overall, nerve roots of the vast majority of patients (48/56, 85.7%) subsided to the ventral side of the dural sac on the prone MR images, although that of 8 (14.3%) patients remain stay in the dorsal side of dural sac. Nerve roots of only one patient with negative SedSign did not settle to the ventral dural sac, while this phenomenon occurred in 7 patients in positive SedSign group (4% vs 22.6%, P < 0.001). In addition, the nerve roots of all the five patients subsided to the left side of dural sac on lateral position MR images.

conclusionsThe nerve roots sedimentation followed the direction of gravity. Positive SedSign may be a MR sign of lumbar pathology involved the spinal canal.

Indexed as

Spinal StenosisCross-Sectional StudiesHumansLumbar VertebraeLumbosacral RegionMagnetic Resonance ImagingSpinal CanalSpinal Nerve RootsGravityLumbar spinal stenosisNerve roots sedimentation signProne position magnetic resonance imaging

Identifiers

PMID33557808
PMCPMC7871597
OpenAlexW3114399860

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.