Evidence map›Paper›PMID 33557777›Full record

ArticleBMC infectious diseases2021

Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province.

Wen Wang, Lei Chen, Qiao He, Mingqi Wang, Mei Liu, Taibing Deng, Xiaoju Deng, Jianrong Yang, Ou Jiang, Rongmei Li and 15 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Frontiers in microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 14 institutions in 1 country.

Wen Wang *Chinese Evidence-based Medicine Center and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Lei Chen *Department of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, 610041, China.
Qiao HeChinese Evidence-based Medicine Center and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Mingqi WangChinese Evidence-based Medicine Center and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Mei LiuChinese Evidence-based Medicine Center and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Taibing DengDepartment of Respiratory Disease, Guang'An Hospital, Guangan, 638001, China.
Xiaoju DengDepartment of Oncology, The People's Hospital of Yuechi, Yuechi, 638300, China.
Jianrong YangDepartment of Infectious Disease, Ganzi Hospital of West China Hospital, Sichuan University, Ganzi, 626000, China.
Ou JiangCancer Center of the Second People's Hospital of Neijiang, Neijiang, 641100, China.
Rongmei LiDepartment of Operation Management, West China Hospital, Sichuan University, Chengdu, 610041, China.
Bo LongDepartment of Infectious Disease, Sichuan Mianyang 404 Hospital, Mianyang, 621000, China.
Gang MaiDepartment of Hepatopancreatobiliary Surgery, People's Hospital of Deyang, Deyang, 618000, China.
Wenhui HuanDepartment of Cardiology, Wusheng County People's Hospital, Guang'an, 638400, China.
Wenquan LiDepartment of Infectious Disease, The Second People's Hospital of Yibin, West China Yibin Hospital, Sichuan University, Yibin, 644000, China.
Xin JiangMianzhu People's Hospital, Mianzhu, 618200, China.
Zeqiang WenDepartment of Thoracic Surgery, The First People's Hospital of Ziyang, Ziyang, 641300, China.
Yongjun ChenDepartment of Gastroenterology, Suining Central Hospital, Suining, 629000, China.
Wanzhi FuDepartment of Infectious Disease, The People's Hospital of Jianyang, Jianyang, 641400, China.
Zhiling LongDepartment of Infectious Disease, Ya'An People's Hospital, Ya'An, 625000, China.
Fanxin ZengDepartment of Clinical Research Center, Dazhou Central Hospital, Dazhou, 635000, China.
Yan ChenDepartment of Respiratory and Critical Care Medicine, Nanchong Central Hospital, Nanchong, 637000, China.
Yihua DuDepartment of Pediatric Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Juan TangDepartment of Infectious Disease, Zigong First People's Hospital, Zigong, 643000, China.
Xin Sun *Chinese Evidence-based Medicine Center and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. sunx79@hotmail.com.
Weimin Li *Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. weimi003@yahoo.com.
Sichuan University · CNSecond People’s Hospital of Yibin · CNAffiliated Hospital of Southwest Medical University · CNDazhou Central Hospital · CNDeyang Stomatological Hospital · CNGuang’anmen Hospital · CNNanchong Central Hospital · CNNeijiang Normal University · CNSichuan Mianyang 404 Hospital · CNSuizhou Central Hospital · CNThe First People's Hospital of Guiyang · CNWest China Hospital of Sichuan University · CNYueqing People's Hospital · CNZigong First People's Hospital · CN

Funding

National Natural Science Foundation of China 71573183the 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University ZYYC08003the Key Research and Development Projects of Science and Technology Department of Sichuan Province 2020YFS0002
6 · The paper itself

Abstract

backgroundThe outbreak of COVID-19 has resulted in serious concerns in China and abroad. To investigate clinical features of confirmed and suspected patients with COVID-19 in west China, and to examine differences between severe versus non-severe patients.

methodsPatients admitted for COVID-19 between January 21 and February 11 from fifteen hospitals in Sichuan Province, China were included. Experienced clinicians trained with methods abstracted data from medical records using pre-defined, pilot-tested forms. Clinical characteristics between severe and non-severe patients were compared.

resultsOf the 169 patients included, 147 were laboratory-confirmed, 22 were suspected. For confirmed cases, the most common symptoms from onset to admission were cough (70·7%), fever (70·5%) and sputum (33·3%), and the most common chest CT patterns were patchy or stripes shadowing (78·0%); throughout the course of disease, 19·0% had no fever, and 12·4% had no radiologic abnormality; twelve (8·2%) received mechanical ventilation, four (2·7%) were transferred to ICU, and no death occurred. Compared to non-severe cases, severe ones were more likely to have underlying comorbidities (62·5% vs 26·2%, P = 0·001), to present with cough (92·0% vs 66·4%, P = 0·02), sputum (60·0% vs 27·9%, P = 0·004) and shortness of breath (40·0% vs 8·2%, P <  0·0001), and to have more frequent lymphopenia (79·2% vs 43·7%, P = 0·003) and eosinopenia (84·2% vs 57·0%, P = 0·046).

conclusionsThe symptoms of patients in west China were relatively mild, and an appreciable proportion of infected cases had no fever, warranting special attention.

Indexed as

AdultAgedChild, PreschoolChinaComorbidityCoughCOVID-19Disease OutbreaksFemaleFeverHospitalizationHumansInfantLungLymphopeniaMaleClinical characteristicsCOVID-19Novel coronavirus

Identifiers

PMID33557777
PMCPMC7868861
OpenAlexW3126745832

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.