Evidence map›Paper›PMID 33557656›Full record

ArticleThe Journal of international medical research2021

Effect of semaphorin 3C gene variants in multifactorial Hirschsprung disease.

Gunadi, Fiko Ryantono, Raman Sethi, Marcellus, Alvin Santoso Kalim, Priscillia Imelda, Devy Melati, Susan Simanjaya, William Widitjiarso, Ririd Tri Pitaka and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

GunadiPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0002-4707-6526
Fiko RyantonoPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Raman SethiDepartment of Pediatrics, National University of Singapore, Singapore and The Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.
MarcellusPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0002-4457-1767
Alvin Santoso KalimPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0002-3313-9063
Priscillia ImeldaPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Devy MelatiPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Susan SimanjayaPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
William WiditjiarsoPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0002-8851-1029
Ririd Tri PitakaPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Nur ArfianDepartment of Anatomy/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Kristy IskandarDepartment of Child Health/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/UGM Academic Hospital, Yogyakarta, Indonesia.
Akhmad MakhmudiPediatric Surgery Division, Department of Surgery/Genetics Working Group, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Poh San LaiDepartment of Pediatrics, National University of Singapore, Singapore and The Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.ORCID https://orcid.org/0000-0003-3352-2000
Universitas Gadjah Mada · IDNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCluster genes, specifically the class 3 semaphorins (

methodsIn this prospective clinical study, we analyzed

resultsTwo variants in

conclusionsThis is the first comprehensive report of

Indexed as

Hirschsprung DiseaseSemaphorinsGenetic Predisposition to DiseaseHumansIndonesiaProspective StudiesProto-Oncogene Proteins c-retProto-Oncogene Proteins c-retSema3C protein, humanSemaphorinsDamaging effect on protein functiondeleterious conservation scorefounder effectHirschsprung diseaseIndonesiapathogenic variantsemaphorin 3C

Identifiers

PMID33557656
PMCPMC7876767
OpenAlexW3127876878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.