Evidence map›Paper›PMID 33557426›Full record

ArticleInternational journal of environmental research and public health2021

Mir-1, miR-122, miR-132, and miR-133 Are Related to Subclinical Aortic Atherosclerosis Associated with Metabolic Syndrome.

Agnė Šatrauskienė, Rokas Navickas, Aleksandras Laucevičius, Tomas Krilavičius, Rūta Užupytė, Monika Zdanytė, Ligita Ryliškytė, Agnė Jucevičienė, Paul Holvoet

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Genes · 2026
    Review
  2. Review
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  4. Article
  5. Therapeutic Applications of Poly-miRNAs and miRNA Sponges.International journal of molecular sciences · 2025
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  7. Review
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  9. Article
  10. Article
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  13. Article
  14. The critical role of epigenetic mechanism in PMGenes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Agnė ŠatrauskienėClinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, 08661 Vilnius, Lithuania.
Rokas NavickasClinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, 08661 Vilnius, Lithuania.ORCID 0000-0002-8258-8009
Aleksandras LaucevičiusClinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, 08661 Vilnius, Lithuania.
Tomas KrilavičiusInformatics Faculty, Vytautas Magnus University, 44248 Kaunas, Lithuania.ORCID 0000-0001-8509-420X
Rūta UžupytėInformatics Faculty, Vytautas Magnus University, 44248 Kaunas, Lithuania.
Monika ZdanytėDepartment of Cardiology and Cardiovascular Medicine, Universität Tübingen, 72074 Tübingen, Germany.
Ligita RyliškytėClinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, 08661 Vilnius, Lithuania.
Agnė JucevičienėClinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, 08661 Vilnius, Lithuania.
Paul HolvoetExperimental Cardiology, Department of Cardiovascular Sciences, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-9201-0772
Vilnius University · LTKU Leuven · BEUniversity of Tübingen · DEVytautas Magnus University · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously, miR-1, miR-122, miR-126, miR-132, miR-133, and miR-370 were found to be related to coronary artery disease (CAD) progression. However, their relationship with subclinical atherosclerosis, especially in subjects with metabolic syndrome, is unknown. Therefore, our aim was to determine their relationship with arterial markers of subclinical atherosclerosis. Metabolic syndrome subjects (n = 182) with high cardiovascular risk but without overt cardiovascular disease (CVD) were recruited from the Lithuanian High Cardiovascular Risk (LitHiR) primary prevention program. The ardio-ankle vascular index (CAVI), augmentation index normalized to a heart rate of 75 bpm (AIxHR75), aortic pulse wave velocity (AoPWV), and carotid artery stiffness were assessed. MicroRNAs (miRs) were analyzed in serum. Pearson correlation and a univariate linear regression

Indexed as

AtherosclerosisMetabolic SyndromeMicroRNAsVascular StiffnessCarotid ArteriesHumansPulse Wave AnalysisMicroRNAsMIRN122 microRNA, humanMIRN132 microRNA, humanMIRN133 microRNA, humanMIRN145 microRNA, humanMIRN1 microRNA, humanMIRN370 microRNA, humanarterial markersdiagnosismetabolic syndromemiRssubclinical atherosclerosis

Identifiers

PMID33557426
PMCPMC7915826
OpenAlexW3126532634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.