ArticleInternational journal of molecular sciences2021
Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- The clinical outcomes of xenografts in the treatment of burn patients: a systematic review and meta-analysis.European journal of medical research · 2023Pooled it
- The Use of Acellular Fish Skin Grafts in Burn Wound Management-A Systematic Review.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Two-stage reconstruction using basic fibroblast growth factor-impregnated artificial dermis and acellular fish skin graft in a dog with distal extremity soft tissue sarcoma.The Journal of veterinary medical science · 2026Article
- The Use of Kerecis Omega3 Wound Fish Skin Graft for the Treatment of Deep Burn Wounds.Plastic and reconstructive surgery. Global open · 2026Article
- Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds.International wound journal · 2026Article
- Advances in Decellularization of Fish Wastes for Extracellular Matrix Extraction in Sustainable Tissue Engineering and Regenerative Medicine.Bioengineering (Basel, Switzerland) · 2026Review
- Clinical Measurement of Transepidermal Water Loss.Advances in wound care · 2026Review
- Polymicrobial Infection (Gram-Positive and Gram-Negative) Exacerbates Systemic Inflammatory Response Syndrome in a Conscious Swine Extremity Trauma Model.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025Article
- From the Ocean to the Operating Room: The Role of Fish Skin Grafts in Burn Management-A Systematic Review.Journal of clinical medicine · 2025Review
- A natural biological adhesive from slug mucus for wound repair.Bioactive materials · 2025Article
- Squid Skin Decellularised Dermal Matrix for Enhancing Repair of Acute Cranial Injuries in Rabbit Model.Journal of functional biomaterials · 2025Article
- Fish Skin Acellular Dermal Matrix Combined With Negative Pressure Wound Therapy for Diabetic Foot Ulcers.Cureus · 2025Article
- Article
- Acellular fish skin grafts in diabetic foot ulcer care: Advances and clinical insights.World journal of diabetes · 2025Article
- Article
- Decellularization of fish tissues for tissue engineering and regenerative medicine applications.Regenerative biomaterials · 2025Review
- Trends in the Treatment of Chronic Wounds.Current medicinal chemistry · 2025Review
- Rapid Healing of Necrotizing Fasciitis Using the Kerecis Fish Skin Xenograft: A Clinical Case Report.Cureus · 2024Article
- Synergistic Treatment of Infected Burn Wound Utilizing Maggot Debridement and Acellular Fish Skin Grafting-A Case Report.Journal of burn care & research : official publication of the American Burn Association · 2024Article
- A Highly Standardized Pre-Clinical Porcine Wound Healing Model Powered by Semi-Automated Histological Analysis.Biomedicines · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
Thermal injuries are caused by exposure to a variety of sources, and split thickness skin grafts are the gold standard treatment for severe burns; however, they may be impossible when there is no donor skin available. Large total body surface area burns leave patients with limited donor site availability and create a need for treatments capable of achieving early and complete coverage that can also retain normal skin function. In this preclinical trial, two cellular and tissue based products (CTPs) are evaluated on twenty-four 5 × 5 deep partial thickness (DPT) burn wounds. Using appropriate pain control methods, DPT burn wounds were created on six anesthetized Yorkshire pigs. Wounds were excised one day post-burn and the bleeding wound beds were subsequently treated with omega-3-rich acellular fish skin graft (FSG) or fetal bovine dermis (FBD). FSG was reapplied after 7 days and wounds healed via secondary intentions. Digital images, non-invasive measurements, and punch biopsies were acquired during rechecks performed on days 7, 14, 21, 28, 45, and 60. Multiple qualitative measurements were also employed, including re-epithelialization, contraction rates, hydration, laser speckle, and trans-epidermal water loss (TEWL). Each treatment produced granulated tissue (GT) that would be receptive to skin grafts, if desired; however, the FSG induced GT 7 days earlier. FSG treatment resulted in faster re-epithelialization and reduced wound size at day 14 compared to FBD (50.2% vs. 23.5% and 93.1% vs. 106.7%,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.