Evidence map›Paper›PMID 33557401›Full record

ReviewBiology2021

Future Approaches for Treating Chronic Myeloid Leukemia: CRISPR Therapy.

Elena Vuelta, Ignacio García-Tuñón, Patricia Hernández-Carabias, Lucía Méndez, Manuel Sánchez-Martín

Open access · goldAbstract readReview
In one paragraph

Review in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. CRISPR/Cas9-Directed Gene Trap Constitutes a Selection System for CorrectedInternational journal of molecular sciences · 2022
    Article
  8. Review
  9. Review
  10. Review
  11. Cell and Gene Therapy for Anemia: Hematopoietic Stem Cells and Gene Editing.International journal of molecular sciences · 2021
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elena VueltaDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-3289-0605
Ignacio García-TuñónInstitute de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0003-4758-2151
Patricia Hernández-CarabiasDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.
Lucía MéndezDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.
Manuel Sánchez-MartínDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-8370-1336
Universidad de Salamanca · ESInstituto de Investigación Biomédica de Salamanca · ES

Funding

Bomberosayudan charity (https://bomberosayudan.org) Jabones solidariosFoundation Memoria Samuel Solórzano Barruso FS/29-20Instituto de Salud Carlos III PI17/01895 (FEDER)
6 · The paper itself

Abstract

The constitutively active tyrosine-kinase

Indexed as

BCR/ABL1CMLCRISPR/Cas9genome editing

Identifiers

PMID33557401
PMCPMC7915349
OpenAlexW3126551654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.