ReviewInternational journal of molecular sciences2021
Neurotrophins Time Point Intervention after Traumatic Brain Injury: From Zebrafish to Human.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
23 citing papers in PubMed, 31 citations in OpenAlex.
- Longitudinal in vivo imaging of dynamic immune-vascular responses to meningeal cerebrovascular injury.Journal of neuroinflammation · 2026Article
- Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish.bioRxiv : the preprint server for biology · 2025Article
- Brain Neurotrophins and Plant Polyphenols: A Powerful Connection.Molecules (Basel, Switzerland) · 2025Review
- Localization of Piezo 1 and Piezo 2 in Lateral Line System and Inner Ear of Zebrafish (International journal of molecular sciences · 2024Article
- Piezo 1 and Piezo 2 in the Chemosensory Organs of Zebrafish (International journal of molecular sciences · 2024Article
- Neurotrophins and neural stem cells in posttraumatic brain injury repair.Animal models and experimental medicine · 2024Review
- Polypathologies and Animal Models of Traumatic Brain Injury.Brain sciences · 2023Review
- Transcription Pattern of Neurotrophic Factors and Their Receptors in Adult Zebrafish Spinal Cord.International journal of molecular sciences · 2023Article
- Cerebrospinal Fluid and Blood Biomarkers in Patients with Post-Traumatic Disorders of Consciousness: A Scoping Review.Brain sciences · 2023Article
- The endogenous progenitor response following traumatic brain injury: a target for cell therapy paradigms.Neural regeneration research · 2022Review
- Saffron Extract Attenuates Anxiogenic Effect and Improves Cognitive Behavior in an Adult Zebrafish Model of Traumatic Brain Injury.International journal of molecular sciences · 2022Article
- A Novel Laser-Based Zebrafish Model for Studying Traumatic Brain Injury and Its Molecular Targets.Pharmaceutics · 2022Article
- The Influence of Neurotrophic Factors BDNF and GDNF Overexpression on the Functional State of Mice and Their Adaptation to Audiogenic Seizures.Brain sciences · 2022Article
- Analysis of the Expression of Neurotrophins and Their Receptors in Adult Zebrafish Kidney.Veterinary sciences · 2022Article
- Ultrastructural Analysis of a Forming Embryonic Embodiment in the Adult Zebrafish Optic Tectum Surviving in Organotypic Culture.NeuroSci · 2022Article
- Expression of Nerve Growth Factor and Its Receptor TrkA in the Reproductive System of Adult Zebrafish.Veterinary sciences · 2022Article
- Localization of BDNF and Calretinin in Olfactory Epithelium and Taste Buds of Zebrafish (International journal of molecular sciences · 2022Article
- Time Course of Changes in the Neurovascular Unit after Hypoxic-Ischemic Injury in Neonatal Rats.International journal of molecular sciences · 2022Article
- The BDNF/TrkB Neurotrophin System in the Sensory Organs of Zebrafish.International journal of molecular sciences · 2022Review
- 3D-printed hyaluronic acid hydrogel scaffolds impregnated with neurotrophic factors (BDNF, GDNF) for post-traumatic brain tissue reconstruction.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traumatic brain injury (TBI) remains the leading cause of long-term disability, which annually involves millions of individuals. Several studies on mammals reported that neurotrophins could play a significant role in both protection and recovery of function following neurodegenerative diseases such as stroke and TBI. This protective role of neurotrophins after an event of TBI has also been reported in the zebrafish model. Nevertheless, reparative mechanisms in mammalian brain are limited, and newly formed neurons do not survive for a long time. In contrast, the brain of adult fish has high regenerative properties after brain injury. The evident differences in regenerative properties between mammalian and fish brain have been ascribed to remarkable different adult neurogenesis processes. However, it is not clear if the specific role and time point contribution of each neurotrophin and receptor after TBI is conserved during vertebrate evolution. Therefore, in this review, I reported the specific role and time point of intervention for each neurotrophic factor and receptor after an event of TBI in zebrafish and mammals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.