ArticleMaterials (Basel, Switzerland)2021
Biological Safety Evaluation and Surface Modification of Biocompatible Ti-15Zr-4Nb Alloy.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Structure-Property-Function Evaluation of a β-Type Ti-Nb-Zr Alloy for Dental Implant Applications with Short-Term Clinical Validation.Journal of functional biomaterials · 2026Article
- Dental Implants: Modern Materials and Methods of Their Surface Modification.Materials (Basel, Switzerland) · 2023Review
- Osseointegration of Tantalum Trabecular Metal in Titanium Dental Implants: Histological and Micro-CT Study.Journal of functional biomaterials · 2023Article
- Zinc-Based Biodegradable Materials for Orthopaedic Internal Fixation.Journal of functional biomaterials · 2022Review
- New Prospects in Nano Phased Co-substituted Hydroxyapatite Enrolled in Polymeric Nanofiber Mats for Bone Tissue Engineering Applications.Annals of biomedical engineering · 2021Review
- Tailoring a Low Young Modulus for a Beta Titanium Alloy by Combining Severe Plastic Deformation with Solution Treatment.Materials (Basel, Switzerland) · 2021Article
- Thermodynamic Assessment of Bio-Oriented Ti-Ta-Sn System.Materials (Basel, Switzerland) · 2021Article
- Mechanical Performance of Artificial Hip Stems Manufactured by Hot Forging and Selective Laser Melting Using Biocompatible Ti-15Zr-4Nb Alloy.Materials (Basel, Switzerland) · 2021Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We performed biological safety evaluation tests of three Ti-Zr alloys under accelerated extraction condition. We also conducted histopathological analysis of long-term implantation of pure V, Al, Ni, Zr, Nb, and Ta metals as well as Ni-Ti and high-V-containing Ti-15V-3Al-3Sn alloys in rats. The effect of the dental implant (screw) shape on morphometrical parameters was investigated using rabbits. Moreover, we examined the maximum pullout properties of grit-blasted Ti-Zr alloys after their implantation in rabbits. The biological safety evaluation tests of three Ti-Zr alloys (Ti-15Zr-4Nb, Ti-15Zr-4Nb-1Ta, and Ti-15Zr-4Nb-4Ta) showed no adverse (negative) effects of either normal or accelerated extraction. No bone was formed around the pure V and Ni implants. The Al, Zr, Nb, and Ni-Ti implants were surrounded by new bone. The new bone formed around Ti-Ni and high-V-containing Ti alloys tended to be thinner than that formed around Ti-Zr and Ti-6Al-4V alloys. The rate of bone formation on the threaded portion in the Ti-15Zr-4Nb-4Ta dental implant was the same as that on a smooth surface. The maximum pullout loads of the grit- and shot-blasted Ti-Zr alloys increased linearly with implantation period in rabbits. The pullout load of grit-blasted Ti-Zr alloy rods was higher than that of shot-blasted ones. The surface roughness (
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