Evidence map›Paper›PMID 33557302›Full record

ArticleNutrients2021

The Gut Microbiome and Metabolomics Profiles of Restricting and Binge-Purging Type Anorexia Nervosa.

Alessio Maria Monteleone, Jacopo Troisi, Gloria Serena, Alessio Fasano, Riccardo Dalle Grave, Giammarco Cascino, Francesca Marciello, Simona Calugi, Giovanni Scala, Giulio Corrivetti and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Metabolomics of testosterone enanthate administration during severe-energy deficit.Metabolomics : Official journal of the Metabolomic Society · 2022
    Trial
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  18. The human microbiome in disease and pathology.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Alessio Maria MonteleoneDepartment of Psychiatry, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-6786-4458
Jacopo TroisiTheoreo srl, Via Degli Ulivi 3, 84090 Montecorvino Pugliano, Italy.ORCID 0000-0003-2962-7379
Gloria SerenaMucosal Immunology and Biology Research Center, Massachusetts General Hospital-Harvard Medical School, Boston, MA 02114, USA.
Alessio FasanoEuropean Biomedical Research Institute of Salerno (EBRIS), Via S. De Renzi, 3, 84125 Salerno, Italy.ORCID 0000-0002-2134-0261
Riccardo Dalle GraveDepartment of Eating and Weight Disorders, Villa Garda Hospital, Garda, 37016 Verona, Italy.ORCID 0000-0002-9796-3721
Giammarco CascinoDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", Neuroscience Section, University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0003-0358-8594
Francesca MarcielloDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", Neuroscience Section, University of Salerno, 84081 Baronissi, Italy.
Simona CalugiDepartment of Eating and Weight Disorders, Villa Garda Hospital, Garda, 37016 Verona, Italy.
Giovanni ScalaTheoreo srl, Via Degli Ulivi 3, 84090 Montecorvino Pugliano, Italy.
Giulio CorrivettiEuropean Biomedical Research Institute of Salerno (EBRIS), Via S. De Renzi, 3, 84125 Salerno, Italy.
Palmiero MonteleoneDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", Neuroscience Section, University of Salerno, 84081 Baronissi, Italy.
University of Salerno · ITCasa di Cura Villa Garda · ITEuropean Biomedical Research Institute of Salerno · ITHarvard University · USUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in the gut microbiome and fecal metabolites have been detected in anorexia nervosa (AN), but differences in those profiles between restricting AN (ANR) and binge-purging AN (ANBP) type have not been explored. We made a secondary analysis of our previous data concerning microbiome and metabolomics profiles of 17 ANR women, six ANBP women and 20 healthy controls (HC). Twelve fecal metabolites differentiating ANR patients, ANBP patients and HC were identified. Both patient groups showed decreased intra-individual bacterial richness with respect to healthy controls (HC). Compared to ANR subjects, ANBP patients had a significant increase in relative abundances of

Indexed as

AdultAnorexia NervosaFecesFemaleGastrointestinal MicrobiomeHumansMetabolomicsYoung Adultbinge-purging anorexia nervosaeating disordersfecal metabolomicsgut microbiomerestricting anorexia nervosa

Identifiers

PMID33557302
PMCPMC7915851
OpenAlexW3128160198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.