Evidence map›Paper›PMID 33557248›Full record

ArticleInternational journal of molecular sciences2021

Potential Protection Effect of ER Homeostasis of N

Charng-Cherng Chyau, Huei-Lin Wu, Chiung-Chi Peng, Shiau-Huei Huang, Chin-Chu Chen, Cheng-Hsu Chen, Robert Y Peng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Evaluation of the Impact ofInternational journal of medical sciences · 2026
    Article
  2. Review
  3. Review
  4. Preventative Effects ofNutrients · 2023
    Article
  5. Article
  6. Amelioration of Cyclosporine A-Induced Acute Nephrotoxicity byInternational journal of molecular sciences · 2023
    Article
  7. Styrylpyrones fromAntioxidants (Basel, Switzerland) · 2022
    Article
  8. Review
  9. Review
  10. Frontiers in pharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Charng-Cherng ChyauResearch Institute of Biotechnology, Hungkuang University, Taichung 43302, Taiwan.ORCID 0000-0001-6801-5573
Huei-Lin WuResearch Institute of Biotechnology, Hungkuang University, Taichung 43302, Taiwan.
Chiung-Chi PengGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.
Shiau-Huei HuangResearch Institute of Biotechnology, Hungkuang University, Taichung 43302, Taiwan.
Chin-Chu ChenGrape King Biotechnology Center, Chung-Li City 320054, Taiwan.
Cheng-Hsu ChenDepartment of Nephrology, Taichung Veterans General Hospital, Taichung 40705, Taiwan.ORCID 0000-0002-1299-5055
Robert Y PengResearch Institute of Biotechnology, Hungkuang University, Taichung 43302, Taiwan.
Hungkuang University · TWGrape King (Taiwan) · TWTaipei Medical University · TW

Funding

Hung-Kuang University TCVGH-HK1088004Taichung Veterans General Hospital TCVGH-HK1088004
6 · The paper itself

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) belong to a class of universally and commonly used anti-inflammatory analgesics worldwide. A diversity of drawbacks of NSAIDs have been reported including cellular oxidative stress, which in turn triggers the accumulation of unfolded proteins, enhancing endoplasmic reticulum stress, and finally resulting in renal cell damage.

Indexed as

HomeostasisAdenosineAnti-Inflammatory Agents, Non-SteroidalCordycepsEndoplasmic Reticulum Chaperone BiPEndoplasmic Reticulum StressGene Expression RegulationHumansKidney Tubules, ProximalOxidative StressProtective AgentsAdenosineAnti-Inflammatory Agents, Non-SteroidalEndoplasmic Reticulum Chaperone BiPHSPA5 protein, humanN6-(2-hydroxyethyl)adenosineProtective Agentsdiclofenacendoplasmic reticulum (ER)meloxicamoxidative stressrenal HK–2 cells

Identifiers

PMID33557248
PMCPMC7913954
OpenAlexW3126934250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.