Evidence map›Paper›PMID 33557147›Full record

ArticleInfectious disease reports2021

Presence of SARS-CoV-2 RNA in Semen-Cohort Study in the United States COVID-19 Positive Patients.

Bruno Machado, Gustavo Barcelos Barra, Nickolas Scherzer, Jack Massey, Hemerson Dos Santos Luz, Rafael Henrique Jacomo, Ticiane Herinques Santa Rita, Rodney Davis

Open access · goldAbstract read
In one paragraph

Article in Infectious disease reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 6 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 6 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Urological complications of COVID-19: a systematic review.International braz j urol : official journal of the Brazilian Society of Urology
    Pooled it
  7. Review
  8. Article
  9. SARS-CoV-2 and reproductive system: a scientometric study.Frontiers in reproductive health · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. SARS-CoV-2 and male infertility: from short- to long-term impacts.Journal of endocrinological investigation · 2023
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Bruno MachadoUrology Department, School of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0003-4653-2267
Gustavo Barcelos BarraClinical Analisys Laboratory, Sabin Medicina Diagnostica, Brasilia, DF 70632-340, Brazil.ORCID 0000-0002-2136-3471
Nickolas ScherzerUrology Department, School of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Jack MasseyUrology Department, School of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Hemerson Dos Santos LuzInfectious Disease Division, Hospital das Forças Armadas, Brasilia, DF 70675-731, Brazil.
Rafael Henrique JacomoClinical Analisys Laboratory, Sabin Medicina Diagnostica, Brasilia, DF 70632-340, Brazil.
Ticiane Herinques Santa RitaClinical Analisys Laboratory, Sabin Medicina Diagnostica, Brasilia, DF 70632-340, Brazil.
Rodney DavisUrology Department, School of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
University of Arkansas for Medical Sciences · USSabin Medicina Diagnostica (Brazil) · BRHospital Nossa Senhora das Graças · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On 31 December 2019, China informed the World Health Organization they were facing a viral pneumonia epidemic of a new type of Coronavirus. Currently, 10 months later, more than 43,000,000 people have been infected, and about 1,150,000 deceased worldwide from the disease. Knowledge about the virus is updated daily, and its RNA was isolated from several human secretions, e.g., throat, saliva, pulmonary alveolar washing, and feces. So far, only one publication found the presence of SARS-CoV-2 in semen. In this 5-month cross-sectional study, we recruited 15 patients diagnosed with a positive nasal swab for SARS-CoV-2 with no or mild symptoms in our institution. A semen sample after a shower was retrieved and tested for viral RNA in the semen. The samples were tested for the viral RNA with RT-PCR with two different genetic probes. The samples were re-tested 24 h after the first test to confirm the results. The SARS-Cov-2 viral RNA was present in 1/15 patients [6.66%] in our sample. Even in a small sample, the RNA from SARS-CoV-2 can be isolated from human semen. This information should alert the scientific community and public health officials about a possible new form of transmission of the disease and long-term clinical effects on the population.

Indexed as

COVID-19SARS-CoV-2Semen

Identifiers

PMID33557147
PMCPMC7930957
OpenAlexW3128089561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.