Evidence map›Paper›PMID 33557136›Full record

ArticleMolecules (Basel, Switzerland)2021

Design, Synthesis, and In Silico Multitarget Pharmacological Simulations of Acid Bioisosteres with a Validated In Vivo Antihyperglycemic Effect.

Elix Alberto Domínguez-Mendoza, Yelzyn Galván-Ciprés, Josué Martínez-Miranda, Cristian Miranda-González, Blanca Colín-Lozano, Emanuel Hernández-Núñez, Gloria I Hernández-Bolio, Oscar Palomino-Hernández, Gabriel Navarrete-Vazquez

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Identification and In Silico Characterization of NovelMolecules (Basel, Switzerland) · 2021
    Article
  6. Dual-Target Compounds against Type 2Pharmaceuticals (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elix Alberto Domínguez-MendozaFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, Mexico.
Yelzyn Galván-CiprésFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, Mexico.
Josué Martínez-MirandaFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, Mexico.
Cristian Miranda-GonzálezFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, Mexico.
Blanca Colín-LozanoFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, Mexico.
Emanuel Hernández-NúñezCátedra CONACyT, Departamento de Recursos del Mar, Centro de Investigación y de Estudios Avanzados, IPN, Unidad Mérida, Yucatan 97310, Mexico.ORCID 0000-0002-7467-7538
Gloria I Hernández-BolioCátedra CONACyT, Departamento de Recursos del Mar, Centro de Investigación y de Estudios Avanzados, IPN, Unidad Mérida, Yucatan 97310, Mexico.ORCID 0000-0002-4979-8979
Oscar Palomino-HernándezComputational Biomedicine (IAS-5/INM-9), Forschungszentrum Juelich, 52425 Julich, Germany.
Gabriel Navarrete-VazquezFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos 62209, Mexico.ORCID 0000-0001-5344-4762

Funding

Consejo Nacional de Ciencia y Tecnología 252881
6 · The paper itself

Abstract

Substituted phenylacetic (

Indexed as

Computer SimulationDrug DesignMolecular Dynamics SimulationChemistry Techniques, SyntheticHypoglycemic AgentsMolecular Targeted TherapyProtein ConformationReproducibility of ResultsHypoglycemic Agentsdiabetesdrug designmolecular dynamicsmultitarget ligands

Identifiers

PMID33557136
PMCPMC7913794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.