Evidence map›Paper›PMID 33557092›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Local Bone Mineral Density, Subcutaneous and Visceral Adipose Tissue Measurements in Routine Multi Detector Computed Tomography-Which Parameter Predicts Incident Vertebral Fractures Best?

Egon Burian, Lioba Grundl, Tobias Greve, Daniela Junker, Nico Sollmann, Maximilian Löffler, Marcus R Makowski, Claus Zimmer, Jan S Kirschke, Thomas Baum

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. CT image-based biomarkers for opportunistic screening of osteoporotic fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Egon BurianDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0003-0428-8569
Lioba GrundlDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Tobias GreveDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0003-2973-5687
Daniela JunkerDepartment of Diagnostic and Interventional Radiology, Klinikum Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Nico SollmannDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0002-8120-2223
Maximilian LöfflerDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0002-6022-3682
Marcus R MakowskiDepartment of Diagnostic and Interventional Radiology, Klinikum Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Claus ZimmerDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Jan S KirschkeDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0002-7557-0003
Thomas BaumDepartment of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0002-4574-5212
TUM Klinikum · DE

Funding

Deutsche Forschungsgemeinschaft 432290010
6 · The paper itself

Abstract

In this case-control study the value of bone mineral density (BMD) at different vertebral levels, subcutaneous adipose tissue (SAT), and visceral adipose tissue (VAT) to identify patients with incident osteoporotic vertebral fractures in routine multi-detector computed tomography (MDCT) exams was assessed. MATERIAL AND

methodsSeventeen patients who underwent baseline and follow-up routine contrast-enhanced MDCT and had an incident osteoporotic vertebral fracture at follow-up were included. Seventeen age-, sex- and follow-up duration-matched controls were identified. Trabecular BMD (from Th5 to L5) as well as cross-sectional area of SAT and VAT were extracted.

resultsBMD performed best to differentiate patients with an incident fracture from controls at the levels of Th5 (area under the curve [AUC] = 0.781,

conclusionThe local BMD measurement appears to be more suitable than standard mean BMD from L1-L3 for fracture risk assessment.

Indexed as

BMDCTincident vertebral fracturesosteoporosisSATVAT

Identifiers

PMID33557092
PMCPMC7913817
OpenAlexW3127619325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.