Evidence map›Paper›PMID 33556483›Full record

ArticleMagnetic resonance imaging2021

Relationships between spinal cord blood flow measured with flow-sensitive alternating inversion recovery (FAIR) and neurobehavioral outcomes in rat spinal cord injury.

Seongtaek Lee, Natasha Wilkins, Brian D Schmit, Shekar N Kurpad, Matthew D Budde

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Seongtaek LeeDepartment of Biomedical Engineering, Marquette University & Medical College of Wisconsin, Milwaukee, WI, United States of America; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States of America. Electronic address: seolee@mcw.edu.
Natasha WilkinsDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States of America.
Brian D SchmitDepartment of Biomedical Engineering, Marquette University & Medical College of Wisconsin, Milwaukee, WI, United States of America.
Shekar N KurpadDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States of America; Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI, United States of America.
Matthew D BuddeDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States of America; Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI, United States of America.
Medical College of Wisconsin · USMarquette University · USMilwaukee VA Medical Center · US

Funding

Noninvasive Spinal Cord Perfusion Techniques with MRIR01NS109090 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI BUDDE, MATTHEW D · 2019 to 2023
$1.7M
NINDS NIH HHS R01 NS109090
6 · The paper itself

Abstract

In the traumatically injured spinal cord, decreased perfusion is believed to contribute to secondary tissue damage beyond the primary mechanical impact, and restoration of perfusion is believed to be a promising therapeutic target. However, methods to monitor spinal cord perfusion non-invasively are limited. Perfusion magnetic resonance imaging (MRI) techniques established for the brain have not been routinely adopted to the spinal cord. The purpose of this study was to examine the relationship between spinal cord blood flow (SCBF) and injury severity in a rat thoracic spinal cord contusion injury (SCI) model using flow-sensitive alternating inversion recovery (FAIR) with two variants of the label position. SCBF as a marker of severity was compared to T

Indexed as

Behavior, AnimalHemodynamicsAnimalsMagnetic Resonance ImagingMaleRatsSpinal CordSpinal Cord InjuriesAnd T(1)-relaxation timeArterial spin labeling (ASL)Flow-sensitive alternating inversion recovery (FAIR)Spinal cord blood flow (SCBF)Spinal cord injury (SCI)

Identifiers

PMID33556483
PMCPMC8501290
OpenAlexW3128662902

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.