Evidence map›Paper›PMID 33556304›Full record

ArticleUrology research & practice2023

Infertility as a Proxy of Men's Health: Still a Long Way to Go.

Edoardo Pozzi, Luca Boeri, Paolo Capogrosso, Luigi Candela, Walter Cazzaniga, Federico Belladelli, Antonio Costa, Daniele Cignoli, Costantino Abbate, Francesco Montorsi and 1 more

Abstract read
In one paragraph

Article in Urology research & practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Edoardo PozziDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy.
Luca BoeriDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy; Department of Urology, Foundation IRCCS Ca' Granda-Ospedale Maggiore Policlinico, University of Milano, Milano, Italy.
Paolo CapogrossoDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy; Department of Urology and Andrology; Ospedale di Circolo and Macchi Foundation, Varese Italy.
Luigi CandelaDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy; University Vita-Salute San Raffaele, Milano, Italy.
Walter CazzanigaDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy; University Vita-Salute San Raffaele, Milano, Italy.
Federico BelladelliDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy.
Antonio CostaDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy; University Vita-Salute San Raffaele, Milano, Italy.
Daniele CignoliDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy; University Vita-Salute San Raffaele, Milano, Italy.
Costantino AbbateDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy.
Francesco MontorsiDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy; University Vita-Salute San Raffaele, Milano, Italy.
Andrea SaloniaDivision of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milano, Italy; University Vita-Salute San Raffaele, Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male infertility (MI) has been widely associated with the development of certain comorbidities and to a lower overall general health status. Higher risks of developing oncological, autoimmune, and chronic disorders among infertile individuals have led researchers to further investigate this issue. Recent clinical studies have been focusing more onto the concept of general health status and mortality. Overall, it has been postulated and subsequently demonstrated that the coexistence of specific diseases and semen alterations may lead to a decreased lifespan. As in Western countries, fatherhood is increasingly delayed in time, and aging might play an important role as a confounding factor for the after-mentioned statements. Although this holds true, even after adjusting for age, it emerges a worrisome picture regarding MI, lower general health status, and increased mortality. The aim of this nonsystematic narrative review is to provide an overview of the most relevant and recent findings on the topic.

Identifiers

PMID33556304
PMCPMC12481759

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.