Evidence map›Paper›PMID 33556287›Full record

SynthesisThe Journal of asthma : official journal of the Association for the Care of Asthma2022

Asthma and risk of infection, hospitalization, ICU admission and mortality from COVID-19: Systematic review and meta-analysis.

Anthony P Sunjaya, Sabine M Allida, Gian Luca Di Tanna, Christine Jenkins

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Journal of asthma : official journal of the Association for the Care of Asthma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 6 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 6 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Risk of serious COVID-19 outcomes among adults and children with moderate-to-severe asthma: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
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  10. Type 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort.The journal of allergy and clinical immunology. Global · 2025
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  19. Immune Response Dynamics and Biomarkers in COVID-19 Patients.International journal of molecular sciences · 2024
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anthony P SunjayaRespiratory Division, The George Institute for Global Health, Newtown, New South Wales, Australia.ORCID 0000-0003-2257-4374
Sabine M AllidaSchool of Medical Sciences, Faculty of Medicine, The University of New South Wales, Kensington, New South Wales, Australia.
Gian Luca Di TannaSchool of Medical Sciences, Faculty of Medicine, The University of New South Wales, Kensington, New South Wales, Australia.
Christine JenkinsRespiratory Division, The George Institute for Global Health, Newtown, New South Wales, Australia.
UNSW Sydney · AUConcord Repatriation General Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAs COVID-19 spreads across the world, there are concerns that people with asthma are at a higher risk of acquiring the disease, or of poorer outcomes. This systematic review aimed to summarize evidence on the risk of infection, severe illness and death from COVID-19 in people with asthma. DATA SOURCES AND STUDY SELECTION: A comprehensive search of electronic databases including preprint repositories and WHO COVID-19 database was conducted (until 26 May 2020). Studies reporting COVID-19 in people with asthma were included. For binary outcomes, we performed Sidik-Jonkman random effects meta-analysis. We explored quantitative heterogeneity by subgroup analyses, meta regression and evaluating the I

resultsFifty-seven studies with an overall sample size of 587 280 were included. The prevalence of asthma among those infected with COVID-19 was 7.46% (95% CI = 6.25-8.67). Non-severe asthma was more common than severe asthma (9.61% vs. 4.13%). Pooled analysis showed a 14% risk ratio reduction in acquiring COVID-19 (95% CI = 0.80-0.94;

conclusionThe findings from this study suggest that the prevalence of people with asthma among COVID-19 patients is similar to the global prevalence of asthma. The overall findings suggest that people with asthma have a lower risk than those without asthma for acquiring COVID-19 and have similar clinical outcomes.

Indexed as

AsthmaCOVID-19HospitalizationHumansIntensive Care UnitsSARS-CoV-2coronaviruscritical care medicinemeta-analysisnovel coronavirus 2019respiratory infectionsSevere acute respiratory syndrome coronavirus 2ventilator support

Identifiers

PMID33556287
PMCPMC8022341
OpenAlexW3126464145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.