Evidence map›Paper›PMID 33556117›Full record

ArticlePloS one2021

Exposure and risk factors for COVID-19 and the impact of staying home on Michigan residents.

Kuan-Han H Wu, Whitney E Hornsby, Bethany Klunder, Amelia Krause, Anisa Driscoll, John Kulka, Ryan Bickett-Hickok, Austin Fellows, Sarah Graham, Erin O Kaleba and 8 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Occurrence of COVID-19 and serumGlobal epidemiology · 2024
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  8. Surveillance for SARS-CoV-2 in Norway Rats (Transboundary and emerging diseases · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Kuan-Han H WuDepartment of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, United States of America.
Whitney E HornsbyDivision of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States of America.ORCID 0000-0002-0672-0338
Bethany KlunderDivision of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States of America.
Amelia KrauseDivision of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States of America.
Anisa DriscollData Office for Clinical & Translational Research, Michigan Medicine Office of Research, Ann Arbor, MI, United States of America.
John KulkaPrecision Health Initiative, University of Michigan, Ann Arbor, MI, United States of America.
Ryan Bickett-HickokPrecision Health Initiative, University of Michigan, Ann Arbor, MI, United States of America.
Austin FellowsPrecision Health Initiative, University of Michigan, Ann Arbor, MI, United States of America.
Sarah GrahamDivision of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States of America.
Erin O KalebaData Office for Clinical & Translational Research, Michigan Medicine Office of Research, Ann Arbor, MI, United States of America.
Salim S HayekDivision of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States of America.ORCID 0000-0003-0180-349X
Xu ShiDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, United States of America.
Nadia R SuttonDivision of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States of America.
Nicholas DouvilleDepartment of Anesthesiology, Michigan Medicine, Ann Arbor, MI, United States of America.
Bhramar MukherjeeDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, United States of America.
Kenneth JamersonDivision of Cardiovascular Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States of America.
Chad M BrummettDepartment of Anesthesiology, Michigan Medicine, Ann Arbor, MI, United States of America.
Cristen J WillerDepartment of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, United States of America.
Michigan Medicine · USUniversity of Michigan · US

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Cell Interactions in the Inflamed Intestinal MucosaR01DK075787 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI JOEL N HIRSCHHORN · 2007 to 2026
$13.1M
Using genetics to discover mechanisms of myocardial infarctionR01HL109946 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YUQING Eugene CHEN, Ida Liisa Surakka · 2011 to 2026
$8.9M
Using Genetics to Inform Mechanism of Cardiovascular DiseaseR35HL135824 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILLER, CRISTEN J · 2017 to 2022
$5.4M
Training Program in BioinformaticsT32GM070449 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ATHEY, BRIAN DAVID, BURMEISTER, MARGIT · 2005 to 2020
$3.6M
Role of SuPAR in the Intersection between Cardiovascular and Kidney DiseaseR01HL153384 · NHLBI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI HAYEK, SALIM · 2020 to 2024
$2.5M
Integrative analysis to uncover biology of blood lipids & coronary heart diseaseR01HL142023 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILLER, CRISTEN J, ZHOU, XIANG · 2018 to 2019
$859k
NHLBI NIH HHS R01 HL109946NHLBI NIH HHS R01 HL142023NHLBI NIH HHS R01 HL153384NHLBI NIH HHS R35 HL135824NIA NIH HHS P30 AG024824NIDDK NIH HHS R01 DK075787NIGMS NIH HHS T32 GM070449
6 · The paper itself

Abstract

COVID-19 has had a substantial impact on clinical care and lifestyles globally. The State of Michigan reports over 80,000 positive COVID-19 tests between March 1, 2020 and July 29, 2020. We surveyed 8,041 Michigan Medicine biorepository participants in late June 2020. We found that 55% of COVID-19 cases reported no known exposure to family members or to someone outside the house diagnosed with COVID-19. A significantly higher rate of COVID-19 cases were employed as essential workers (45% vs 19%, p = 9x10-12). COVID-19 cases reporting a fever were more likely to require hospitalization (categorized as severe; OR = 4.4 [95% CI: 1.6-12.5, p = 0.005]) whereas respondents reporting rhinorrhea was less likely to require hospitalization (categorized as mild-to-moderate; OR = 0.16 [95% CI: 0.04-0.73, p = 0.018]). African-Americans reported higher rates of being diagnosed with COVID-19 (OR = 4.0 [95% CI: 2.2-7.2, p = 5x10-6]), as well as higher rates of exposure to family or someone outside the household diagnosed with COVID-19, an annual household income < $40,000, living in rental housing, and chronic diseases. During the Executive Order in Michigan, African Americans, women, and the lowest income group reported worsening health behaviors and higher overall concern for the potential detrimental effects of the pandemic. The higher risk of contracting COVID-19 observed among African Americans may be due to the increased rates of working as essential employees, lower socioeconomic status, and exposure to known positive cases. Continued efforts should focus on COVID-19 prevention and mitigation strategies, as well as address the inequality gaps that result in higher risks for both short-term and long-term health outcomes.

Indexed as

Communicable Disease ControlAdultAgedBlack or African AmericanComorbidityCOVID-19FemaleHumansMaleMichiganMiddle AgedRisk FactorsSocioeconomic FactorsSurveys and QuestionnairesTravel

Identifiers

PMID33556117
PMCPMC7870003
OpenAlexW3128477556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.