Evidence map›Paper›PMID 33555999›Full record

ArticleeLife2021

Single-cell transcriptomes of developing and adult olfactory receptor neurons in

Colleen N McLaughlin, Maria Brbić, Qijing Xie, Tongchao Li, Felix Horns, Sai Saroja Kolluru, Justus M Kebschull, David Vacek, Anthony Xie, Jiefu Li and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 128 citations in OpenAlex.

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  10. Organization and evolution of sex-biased gene expression inbioRxiv : the preprint server for biology · 2026
    Article
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  12. Review
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  19. A single-nucleus transcriptomic atlas of the adultbioRxiv : the preprint server for biology · 2025
    Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Colleen N McLaughlin *Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.ORCID 0000-0002-7518-8920
Maria Brbić *Department of Computer Science, Stanford University, Stanford, United States.ORCID 0000-0002-1120-1778
Qijing XieDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.ORCID 0000-0002-0997-8326
Tongchao LiDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Felix HornsDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0001-5872-5061
Sai Saroja KolluruDepartment of Bioengineering, Stanford University, Stanford, United States.
Justus M KebschullDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
David VacekDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Anthony XieDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Jiefu LiDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.ORCID 0000-0002-0062-4652
Robert C JonesDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0001-7235-9854
Jure LeskovecDepartment of Computer Science, Stanford University, Stanford, United States.
Stephen R QuakeDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0002-1613-0809
Liqun LuoDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.ORCID 0000-0001-5467-9264
Hongjie LiDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Howard Hughes Medical Institute · USStanford University · USChan Zuckerberg Initiative (United States) · US

Funding

Assembly of the Central Olfactory Networks in DrosophilaR01DC005982 · NIDCD · STANFORD UNIVERSITY · PI LIQUN LUO · 2003 to 2026
$8.1M
Characterizing the assembly and age-related decline of neural circuits in Drosophila by single-cell profilingK99AG062746 · NIA · STANFORD UNIVERSITY · PI LI, HONGJIE · 2019 to 2020
$254k
Howard Hughes Medical InstituteNIA NIH HHS K99 AG062746NIDCD NIH HHS R01 DC005982NIH HHS K99 AG062746
6 · The paper itself

Abstract

Recognition of environmental cues is essential for the survival of all organisms. Transcriptional changes occur to enable the generation and function of the neural circuits underlying sensory perception. To gain insight into these changes, we generated single-cell transcriptomes of

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsFemaleMaleOlfactory Receptor NeuronsSequence Analysis, RNASingle-Cell AnalysisSmellTranscriptomeDrosophila ProteinsD. melanogasterDrosophilaneuroscienceolfactory receptorolfactory receptor neuronolfactory systemsingle-cell RNA-seqsingle-nucleus RNA-seq

Identifiers

PMID33555999
PMCPMC7870146
OpenAlexW3127332899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.