Evidence map›Paper›PMID 33555612›Full record

ReviewImmunology2021

Monocytes, macrophages, dendritic cells and neutrophils: an update on lifespan kinetics in health and disease.

Amit A Patel, Florent Ginhoux, Simon Yona

Open access · bronzeAbstract readReview
In one paragraph

Review in Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 207 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Nanomaterials Drive In Vivo CAR Immune Cells Engineering.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  5. Monocyte-Amplified Transcriptional Signatures of Human Diseases.bioRxiv : the preprint server for biology · 2026
    Article
  6. Review
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  10. Review
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  14. Review
  15. Article
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  18. Review
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  20. Review

70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 5 countries.

Amit A PatelInserm U1015, Gustave Roussy, Villejuif, France.ORCID 0000-0003-4961-0347
Florent GinhouxSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Simon YonaInstitute of Dental Sciences, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel.
Agency for Science, Technology and Research · SGHebrew University of Jerusalem · ILInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phagocytes form a family of immune cells that play a crucial role in tissue maintenance and help orchestrate the immune response. This family of cells can be separated by their nuclear morphology into mononuclear and polymorphonuclear phagocytes. The generation of these cells in the bone marrow, to the blood and finally into tissues is a tightly regulated process. Ensuring the adequate production of these cells and their timely removal is key for both the initiation and resolution of inflammation. Insight into the kinetic profiles of innate myeloid cells during steady state and pathology will permit the rational development of therapies to boost the production of these cells in times of need or reduce them when detrimental.

Indexed as

AnimalsDendritic CellsHomeostasisHumansImmunity, InnateInflammationMacrophagesMonocytesMononuclear Phagocyte SystemNeutrophilshomeostasisinflammationkineticsmononuclear phagocyteneutrophils

Identifiers

PMID33555612
PMCPMC8207393
OpenAlexW3126766007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.