Evidence map›Paper›PMID 33555595›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Development of a huBLT Mouse Model to Study HCMV Latency, Reactivation, and Immune Response.

Lindsey B Crawford, Patrizia Caposio

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Viral and host network analysis of the human cytomegalovirus transcriptome in latency.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Immune Prophylaxis and Therapy for Human Cytomegalovirus Infection.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lindsey B CrawfordVaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, OR, USA.
Patrizia CaposioVaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, OR, USA. caposiop@ohsu.edu.
Oregon Health & Science University · US

Funding

The Administrative CoreP01AI127335 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Patrizia Caposio · 2017 to 2026
$24.6M
NIAID NIH HHS P01 AI127335
6 · The paper itself

Abstract

Immunodeficient mice engrafted with human tissues provide a robust model for the in vivo investigation of human-restricted viruses such as human cytomegalovirus (HCMV). Several humanized mouse models have been developed and improved over the last 30 years. Here, we describe a protocol for the transplant of human hematopoietic stem cells with autologous fetal liver and thymic tissues into NOD.Cg-Prkdc

Indexed as

Disease Models, AnimalAdaptive ImmunityAnimalsB-LymphocytesCD8-Positive T-LymphocytesCytomegalovirusCytomegalovirus InfectionsHematopoietic Stem CellsHematopoietic Stem Cell TransplantationHumansMiceMice, Inbred NODMice, SCIDB-cell responseHematopoietic progenitor cellshuBLTHuman CytomegalovirusHumanized miceT-cell responseThymus

Identifiers

PMID33555595
OpenAlexW3127333155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.