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ArticleIndian journal of pediatrics2021

Clinicoepidemiological Profile and Genetic Characterization of Circulating Rotavirus Strain among Children < 5 Years Hospitalized for Acute Gastroenteritis in Western Rajasthan, India.

Pramod Sharma, Suman Katewa, Suresh Kumar Meel, Vikash Katewa, Alka Bishnoi, Vijay Kumar Verma, Nayana P Nair, Varunkumar Thiyagarajan

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Article in Indian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Information for Action: The Power of Surveillance.Indian journal of pediatrics · 2021
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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Pramod SharmaDepartment of Pediatrics, Dr S N Medical College, Jodhpur, Rajasthan, 342003, India.
Suman KatewaDepartment of Obstetrics & Gynaecology, Dr S N Medical College, Jodhpur, Rajasthan, India.
Suresh Kumar MeelDepartment of Pediatrics, Dr S N Medical College, Jodhpur, Rajasthan, 342003, India.
Vikash KatewaDepartment of Pediatrics, Dr S N Medical College, Jodhpur, Rajasthan, 342003, India. drvikaskatewa@gmail.com.ORCID 0000-0003-2894-0099
Alka BishnoiDepartment of Pediatrics, Dr S N Medical College, Jodhpur, Rajasthan, 342003, India.
Vijay Kumar VermaDepartment of Pediatrics, Dr S N Medical College, Jodhpur, Rajasthan, 342003, India.
Nayana P NairThe Wellcome Trust Research Laboratory, Christian Medical College, Vellore, Tamil Nadu, India.
Varunkumar ThiyagarajanThe Wellcome Trust Research Laboratory, Christian Medical College, Vellore, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the clinical and epidemiological profile and circulating strains of rotavirus among children less than 5 y of age hospitalized for diarrhea in a tertiary care center of western Rajasthan.

methodChildren < 5 y of age admitted for acute gastroenteritis were recruited in this hospital-based surveillance study. Detailed clinical history and sociodemographic information was collected for all enrolled children. Severity of the gastroenteritis was assessed using the 20-point Vesikari Clinical Severity Scoring System. Rotavirus positivity was tested in the stool samples collected from children by commercially available techniques and further molecular characterization done as per defined protocol.

resultsOut of 1055 enrolled children, overall positivity rate of typable rotavirus was 18.95% (169/892). Among children who were less than 24 mo of age, positivity due to rotavirus diarrhea was maximum (24.4%). Distinct seasonality was observed as maximum cases of rotavirus diarrhea were detected in the months of December to February. Commonest G type was G3 (54%) followed by G1 (19%) while predominant P type was P[8] (77%) followed by P[4] (11%). G3P[8] (51.83%) was the commonest genotype observed in the study region.

conclusionThe current study found positivity of rotavirus to be 18.95% among children aged 0-59 mo admitted due to acute gastroenteritis is a tertiary care setting in northern part of India. Emergence of newer predominant strains emphasizes the need of continued surveillance to determine the changing trends.

Indexed as

GastroenteritisRotavirusRotavirus InfectionsAdolescentAdultChildChild, PreschoolDiarrheaFecesGenotypeHumansIndiaInfantInfant, NewbornMiddle AgedYoung AdultEIAGastroenteritisGenotypingG-typeP-typeRotavirus

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.