Evidence map›Paper›PMID 33555426›Full record

ArticleEuropean journal of pediatrics2021

Consequences of coronavirus disease-2019 (COVID-19) lockdown on infection-related hospitalizations among the pediatric population in Denmark.

Laura Bech Polcwiartek, Christoffer Polcwiartek, Mikkel Porsborg Andersen, Lauge Østergaard, Marcella D Broccia, Gunnar H Gislason, Lars Køber, Christian Torp-Pedersen, Morten Schou, Emil Fosbøl and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in European journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06211621 (Admission Pattern Among Children With Gastro-intestinal Infections Before and During the Covid-19 Pandemic), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06211621 completednot on this map

Admission Pattern Among Children With Gastro-intestinal Infections Before and During the Covid-19 Pandemic

TypeobservationalSponsorRegion ZealandRan2017 to 2024Enrolled600ConditionsGastroenteritis, Rota Virus Gastroenteritis, Dehydration in Children, Infectious Disease
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Human Mobility and Droplet-Transmissible Pediatric Infectious Diseases during the COVID-19 Pandemic.International journal of environmental research and public health · 2022
    Article
  8. Article
  9. Article
  10. The impact of COVID-19 pandemic on acute otitis media among the pediatric population.International journal of pediatric otorhinolaryngology · 2022
    Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laura Bech PolcwiartekDepartment of Pediatrics, Aalborg University Hospital, Reberbansgade 15, 9000, Aalborg, Denmark. laurafbech@hotmail.com.ORCID http://orcid.org/0000-0002-1251-6675
Christoffer PolcwiartekDepartment of Cardiology, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Mikkel Porsborg AndersenDepartment of Clinical Research, Nordsjaellands Hospital, Dyrehavevej 29, 3400, Hillerød, Denmark.
Lauge ØstergaardDepartment of Cardiology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Marcella D BrocciaDepartment of Clinical Research, Nordsjaellands Hospital, Dyrehavevej 29, 3400, Hillerød, Denmark.
Gunnar H GislasonThe Danish Heart Foundation, Vognmagergade 7, 3. sal, 1120, Copenhagen, Denmark.
Lars KøberDepartment of Cardiology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Christian Torp-PedersenDepartment of Cardiology, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Morten SchouDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Gentofte Hospitalsvej 1, 2900, Hellerup, Denmark.
Emil FosbølDepartment of Cardiology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Kristian KragholmDepartment of Cardiology, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Søren HagstrømDepartment of Pediatrics, Aalborg University Hospital, Reberbansgade 15, 9000, Aalborg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It remains unknown how Coronavirus disease-2019 (COVID-19) prevention measures implemented on March 12, 2020, have affected the rate of pediatric infection-related hospitalizations in Denmark. Therefore, we investigated the rate of pediatric infection-related hospitalizations during the COVID-19 pandemic. We used a retrospective cohort design and included all Danish children < 18 years. Infection-related hospitalizations were assessed during study periods in 2020 vs. 2018/2019, and we computed incidence rate ratios (IRRs) with 95% confidence intervals (CIs) using Poisson regression. In the 2020 study period, 3093 children were hospitalized with an infection, while the corresponding figures for 2018 and 2019 study periods were 4824 and 3830, respectively. When comparing the 2020 to the 2018/2019 study period prior to nationwide lockdown, we observed a decline in infection-related hospitalizations (12.68 (95% CI, 12.22-13.16) vs. 15.49 (95% CI, 15.12-15.86) per 1000 person-years). We further observed decreased IRRs, especially during the lockdown period (week 11: 0.64 (95% CI, 0.55-0.75); week 12: 0.26 (95% CI, 0.21-0.33); week 13: 0.13 (95% CI, 0.10-0.19)).Conclusion: The rate of pediatric infection-related hospitalizations in Denmark declined during the COVID-19 pandemic in 2020 compared to that in 2018/2019, with a 36% decline during initiation of the nationwide lockdown period. What is Known: • Due to the COVID-19 pandemic, several countries have implemented mitigation strategies such as lockdown of non-critical business functions. Most of these strategies have previously been proven effective on interruption of infection transmission. • It remains unclear how the mitigation strategies have affected the rate of pediatric infection-related hospitalizations. What is New: • Insight on how COVID-19 prevention measures have affected the frequency of infection-related hospitalization. • Valuable knowledge on how to act in potential future pandemics.

Indexed as

COVID-19PandemicsChildCommunicable Disease ControlDenmarkHospitalizationHumansRetrospective StudiesSARS-CoV-2COVID-19EpidemiologyInfectionsPediatric

Identifiers

PMID33555426
PMCPMC7868522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.