Evidence map›Paper›PMID 33555200›Full record

ArticleEnvironmental health perspectives2021

Fine Particle Exposure and Clinical Aggravation in Neurodegenerative Diseases in New York State.

Yanelli Nunez, Amelia K Boehme, Marc G Weisskopf, Diane B Re, Ana Navas-Acien, Aaron van Donkelaar, Randall V Martin, Marianthi-Anna Kioumourtzoglou

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  14. Article
  15. Air Pollution-Related Neurotoxicity Across the Life Span.Annual review of pharmacology and toxicology · 2023
    Review
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yanelli NunezDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Amelia K BoehmeDepartment of Epidemiology and Neurology, Columbia University, New York, New York, USA.
Marc G WeisskopfDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Diane B ReDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Ana Navas-AcienDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Aaron van DonkelaarDepartment of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.
Randall V MartinDepartment of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.
Marianthi-Anna KioumourtzoglouDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Columbia University · USDalhousie University · CAHarvard University · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
GRADUATE TRAINING IN BIOSTATISTICST32ES007142 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$11.9M
National Cohort Studies of Alzheimer's Disease, Related Dementias and Air PollutionR01AG066793 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2020 to 2025
$4.2M
Integrating Air Pollution Prediction Models: Uncertainty Quantification and Propagation in Health StudiesR01ES030616 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DOMINICI, FRANCESCA, KIOUMOURTZOGLOU, MARIANTHI-ANNA · 2020 to 2024
$3.1M
Principal Component Pursuit to Assess Exposure to Environmental Mixtures in Epidemiologic StudiesR01ES028805 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KIOUMOURTZOGLOU, MARIANTHI-ANNA · 2018 to 2021
$2.2M
Air Pollution Exposure and Risk of Amyotrophic Lateral Sclerosis (ALS)R21ES028472 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KIOUMOURTZOGLOU, MARIANTHI-ANNA · 2018 to 2019
$406k
NIA NIH HHS R01 AG066793NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES028805NIEHS NIH HHS R01 ES030616NIEHS NIH HHS R21 ES028472NIEHS NIH HHS T32 ES007142NIEHS NIH HHS T32 ES007322
6 · The paper itself

Abstract

backgroundAdult-onset neurodegenerative diseases affect millions and negatively impact health care systems worldwide. Evidence suggests that air pollution may contribute to aggravation of neurodegeneration, but studies have been limited.

objectiveWe examined the potential association between long-term exposure to particulate matter

methodsWe used data from the New York Department of Health Statewide Planning and Research Cooperative System (SPARCS 2000-2014) to construct annual county counts of first hospitalizations with a diagnosis of AD, PD, or ALS (total, urbanicity-, sex-, and age-stratified). We used annual

resultsWe found a positive nonlinear

conclusionOur findings suggest that annual increase in county-level

Indexed as

Air PollutantsAir PollutionNeurodegenerative DiseasesAdultAgedEnvironmental ExposureHospitalizationHumansNew YorkParticulate MatterAir PollutantsParticulate Matter

Identifiers

PMID33555200
PMCPMC7869948
OpenAlexW3127979955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.